Evidence map›Paper›PMID 28321181›Full record

ArticleFrontiers in cellular neuroscience2017

RNF146 Inhibits Excessive Autophagy by Modulating the Wnt-β-Catenin Pathway in Glutamate Excitotoxicity Injury.

Yuefan Yang, Peng Luo, Haoxiang Xu, Shuhui Dai, Wei Rao, Cheng Peng, Wenke Ma, Jiu Wang, Hongyu Xu, Lei Zhang and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 21 citations in OpenAlex.

  1. Review
  2. Article
  3. Modification of Wnt signaling pathway on paraquat-induced inhibition of neural progenitor cell proliferation.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association · 2018
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Yuefan YangDepartment of Neurosurgery, Xijing Hospital, Fourth Military Medical University Xi'an, China.
Peng LuoDepartment of Neurosurgery, Xijing Hospital, Fourth Military Medical University Xi'an, China.
Haoxiang XuDepartment of Biomedical Engineering, Fourth Military Medical UniversityXi'an, China; Department of Neurosurgery, 411 Hospital of People's Liberation ArmyShanghai, China.
Shuhui DaiDepartment of Neurosurgery, Xijing Hospital, Fourth Military Medical University Xi'an, China.
Wei RaoDepartment of Neurosurgery, Xijing Hospital, Fourth Military Medical University Xi'an, China.
Cheng PengDepartment of Neurosurgery, Xijing Hospital, Fourth Military Medical University Xi'an, China.
Wenke MaDepartment of Neurosurgery, Xijing Hospital, Fourth Military Medical University Xi'an, China.
Jiu WangDepartment of Neurosurgery, Xijing Hospital, Fourth Military Medical University Xi'an, China.
Hongyu XuDepartment of Neurosurgery, Xijing Hospital, Fourth Military Medical University Xi'an, China.
Lei ZhangDepartment of Neurosurgery, Xijing Hospital, Fourth Military Medical University Xi'an, China.
Sai ZhangDepartment of Neurosurgery, Affiliated Hospital of Logistics, University of Chinese Armed Police Forces Tianjin, China.
Zhou FeiDepartment of Neurosurgery, Xijing Hospital, Fourth Military Medical University Xi'an, China.
Xijing Hospital · CNAir Force Medical University · CNLogistics University of People's Armed Police Force · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Glutamate induced excitotoxicity is common in diverse neurological disorders. RNF146 as an E3 ubiquitin ligase protects neurons against excitotoxicity

Indexed as

autophagyexcitotoxicityglutamateRNF146Wnt/β-catenin signaling

Identifiers

PMID28321181
PMCPMC5337692
OpenAlexW2602293454

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.