ArticleWorld journal of gastroenterology2017
Proton pump inhibitor induced collagen expression in colonocytes is associated with collagenous colitis.
Article in World journal of gastroenterology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 19 citations in OpenAlex.
- Paclitaxel-Induced Collagenous Colitis: A Case Report in Male Breast Cancer.Reports (MDPI) · 2025Article
- Update on the Epidemiology and Management of Microscopic Colitis.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2025Review
- Identification and Validation of SLC9A2 as A Potential Tumor Suppressor in Colorectal Cancer: Integrating Bioinformatics Analysis with Experimental Confirmation.Current medical science · 2024Article
- Article
- Lack of autoantibodies against collagen and related proteins in collagenous colitis.BMC immunology · 2022Article
- Diagnosis and Management of Microscopic Colitis in Pediatric Patients.Paediatric drugs · 2022Review
- Insights into the underlying mechanisms and clinical management of microscopic colitis in relation to other gastrointestinal disorders.Gastroenterology report · 2022Review
- Gastroprotective Effect of Enteral Nutrition Formula in Mice Injected Subcutaneously with Indomethacin.Nutrients · 2021Article
- Microscopic colitis.Nature reviews. Disease primers · 2021Review
- Clinical characteristics and factors related to antibiotic-associated diarrhea in elderly patients with pneumonia: a retrospective cohort study.BMC geriatrics · 2021Article
- Controversials of Microscopic Colitis.Frontiers in medicine · 2021Review
- Effect of Proton Pump Inhibitors on Colorectal Cancer.International journal of molecular sciences · 2020Article
- Study of the Inhibitory Effects of Enteral Nutrition Formula on Indomethacin-Induced Gastric Lesions in Mice.Nutrients · 2019Article
- Advantages and Disadvantages of Long-term Proton Pump Inhibitor Use.Journal of neurogastroenterology and motility · 2018Review
- Smoking is Associated with an Increased Risk of Microscopic Colitis: Results From Two Large Prospective Cohort Studies of US Women.Journal of Crohn's & colitis · 2018Article
Corrections and comments
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo elucidate the role of proton pump inhibitors (PPIs) in collagenous disease, direct effect of PPI on colonocytes was examined.
methodsCollagenous colitis is a common cause of non-bloody, watery diarrhea. Recently, there has been increasing focus on the use of proton PPIs as a risk factor for developing collagenous colitis. Mouse CT26 colonic cells were treated with PPI and/or PPI-induced alkaline media. Expression of fibrosis-associated genes was examined by RT-PCR. In human materials, collagen expression was examined by immunohistochemistry.
resultsCT26 cells expressed a Na
conclusionFrom these findings, the reaction of colonocytes to PPI might participate in pathogenesis of collagenous colitis.
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