Evidence map›Paper›PMID 28321152›Full record

ArticleMediators of inflammation2017

Th1/Th17-Related Cytokines and Chemokines and Their Implications in the Pathogenesis of Pemphigus Vulgaris.

Rodolfo Pessato Timoteo, Marcos Vinicius da Silva, Camila Botelho Miguel, Djalma Alexandre Alves Silva, Jonatas Da Silva Catarino, Virmondes Rodrigues Junior, Helioswilton Sales-Campos, Carlo Jose Freire Oliveira

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Mediators of inflammation, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04096222 (Comparative Analysis of the Th17 Cellular Response in Active and Inactive Pemphigus Vulgaris Patients), which is not on this map. Cited by 41 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 1 pooled it
4.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04096222 unknown statusnot on this mapstarted 2021, after this paper: background citation

Comparative Analysis of the Th17 Cellular Response in Active and Inactive Pemphigus Vulgaris Patients

TypeobservationalSponsorInstituto Nacional de Ciencias Medicas y Nutricion Salvador ZubiranRan2021 to 2023Enrolled42ConditionsPemphigus Vulgaris, Bullous Dermatoses, Autoimmune Diseases
3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 1 synthesis or guideline pooled it, 79 citations in OpenAlex.

  1. Pooled it
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  4. Osteoporosis in Pemphigus: Steroids Are Not the Only Story.Dermatology practical & conceptual · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Rodolfo Pessato TimoteoLaboratory of Immunology, Federal University of Triângulo Mineiro, Uberaba, MG, Brazil.
Marcos Vinicius da SilvaLaboratory of Immunology, Federal University of Triângulo Mineiro, Uberaba, MG, Brazil.ORCID 0000-0002-2966-7621
Camila Botelho MiguelLaboratory of Immunology, Federal University of Triângulo Mineiro, Uberaba, MG, Brazil.ORCID 0000-0002-1834-1394
Djalma Alexandre Alves SilvaLaboratory of Immunology, Federal University of Triângulo Mineiro, Uberaba, MG, Brazil.
Jonatas Da Silva CatarinoLaboratory of Immunology, Federal University of Triângulo Mineiro, Uberaba, MG, Brazil.
Virmondes Rodrigues JuniorLaboratory of Immunology, Federal University of Triângulo Mineiro, Uberaba, MG, Brazil.
Helioswilton Sales-CamposLaboratory of Immunology, Federal University of Triângulo Mineiro, Uberaba, MG, Brazil.ORCID 0000-0003-3252-2834
Carlo Jose Freire OliveiraLaboratory of Immunology, Federal University of Triângulo Mineiro, Uberaba, MG, Brazil.ORCID 0000-0003-2211-7333
Universidade Federal do Triângulo Mineiro · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pemphigus vulgaris (PV) is an autoimmune disease characterized by the presence of IgG autoantibodies against desmoglein-3. Despite the variety of findings, the chemokine and cytokine profiles that characterize the immune response in the disease are still poorly explored. Thus, 20 PV patients and 20 controls were grouped according to gender, ethnicity, place of residence, and clinical parameters of the disease. Then, the levels of chemokines and of Th1/Th2/Th17/Treg/Th9/Th22-related cytokines were assessed in the serum. PV patients had higher levels of inflammatory Th1/Th17 cytokines (IFN-

Indexed as

AdultChemokine CCL3Chemokine CCL5ChemokinesCytokinesFemaleHumansInterleukin-2Interleukin-23Interleukin-6Interleukin-8MaleMiddle AgedPemphigusTh17 CellsTh1 CellsChemokine CCL3Chemokine CCL5ChemokinesCytokinesInterleukin-2Interleukin-23Interleukin-6Interleukin-8Tumor Necrosis Factor-alpha

Identifiers

PMID28321152
PMCPMC5340942
OpenAlexW2589439154

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.