ArticleProceedings of the National Academy of Sciences of the United States of America2017
Cerberus-Nodal-Lefty-Pitx signaling cascade controls left
Article in Proceedings of the National Academy of Sciences of the United States of America, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 62 citations in OpenAlex.
- Abalone genomics reveals an ancient asymmetry axis and the multifunctionality of the mantle.Science advances · 2026Article
- Enigmatic Nodal and Lefty gene repertoire discrepancy: Latent evolutionary history revealed by vertebrate-wide phylogeny.Developmental dynamics : an official publication of the American Association of Anatomists · 2025Review
- An amphioxus neurula stage cell atlas supports a complex scenario for the emergence of vertebrate head mesoderm.Nature communications · 2024Article
- Evolution of the gene regulatory network of body axis by enhancer hijacking in amphioxus.eLife · 2024Article
- AmphioxusMarine life science & technology · 2023Article
- Article
- Three amphioxus reference genomes reveal gene and chromosome evolution of chordates.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Highly distinct genetic programs for peripheral nervous system formation in chordates.BMC biology · 2022Article
- Genetic assimilation and the evolution of direction of genital asymmetry in anablepid fishes.Proceedings. Biological sciences · 2022Article
- Article
- Hedgehog signaling controls mouth opening in the amphioxus.Zoological letters · 2021Article
- Crosstalk between nitric oxide and retinoic acid pathways is essential for amphioxus pharynx development.eLife · 2021Article
- Pitx controls amphioxus asymmetric morphogenesis by promoting left-side development and repressing right-side formation.BMC biology · 2021Article
- Pitx genes in development and disease.Cellular and molecular life sciences : CMLS · 2021Review
- Chronic Exposure to Cadmium Induces Differential Methylation in Mice Spermatozoa.Toxicological sciences : an official journal of the Society of Toxicology · 2021Article
- JNK Mediates Differentiation, Cell Polarity and Apoptosis During Amphioxus Development by Regulating Actin Cytoskeleton Dynamics and ERK Signalling.Frontiers in cell and developmental biology · 2021Article
- A Potential Method for Rapid Screening of Amphioxus Founder Harboring Germline Mutation and Transgene.Frontiers in cell and developmental biology · 2021Article
- Article
- Review
- Step-wise evolution of neural patterning by Hedgehog signalling in chordates.Nature ecology & evolution · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Many bilaterally symmetrical animals develop genetically programmed left-right asymmetries. In vertebrates, this process is under the control of Nodal signaling, which is restricted to the left side by
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.