ArticleProceedings of the National Academy of Sciences of the United States of America2017
Highly oriented photosynthetic reaction centers generate a proton gradient in synthetic protocells.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.
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Who cites it
43 citing papers in PubMed, 114 citations in OpenAlex.
- Photocatalytic Biohybrid Vesicles.Chemical reviews · 2026Review
- Reconstituting alternative life using the test-bed of cell-free systems.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2025Review
- Unidirectional Transmembrane Photoinduced Electron Transfer with Artificial Metallopeptides.Artificial photosynthesis (Washington, D.C.) · 2025Article
- Continuous Light-Induced Water Oxidation in Polyoxometalate-Based Photocatalytic Protocells and Prototissues.Chemistry (Weinheim an der Bergstrasse, Germany) · 2025Article
- Towards Synthetic Cells with Self-Producing Energy.ChemPlusChem · 2024Review
- Formation of Cell-Sized Liposomes Incorporating a β-Barrel-Structured Porin through Rehydration of a Phospholipid-Membrane Protein Dried Film.ACS omega · 2024Article
- Synthetic Cells Revisited: Artificial Cells Construction Using Polymeric Building Blocks.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Review
- Bioinspired photocatalytic systems towards compartmentalized artificial photosynthesis.Communications chemistry · 2023Review
- The protometabolic nature of prebiotic chemistry.Chemical Society reviews · 2023Review
- Calcium-triggered DNA-mediated membrane fusion in synthetic cells.Chemical communications (Cambridge, England) · 2023Article
- Calcium-triggered DNA-mediated membrane fusion in synthetic cells.bioRxiv : the preprint server for biology · 2023Article
- DNA-Origami Line-Actants Control Domain Organization and Fission in Synthetic Membranes.Journal of the American Chemical Society · 2023Article
- Function Investigations and Applications of Membrane Proteins on Artificial Lipid Membranes.International journal of molecular sciences · 2023Review
- Cell-sized asymmetric phospholipid-amphiphilic protein vesicles with growth, fission, and molecule transportation.iScience · 2023Article
- Artificial organelles for sustainable chemical energy conversion and production in artificial cells: Artificial mitochondrion and chloroplasts.Biophysics reviews · 2023Review
- Light energy transduction in liposome-based artificial cells.Frontiers in bioengineering and biotechnology · 2023Review
- Artificial cell design: reconstructing biology for life science applications.Emerging topics in life sciences · 2022Review
- Experimental platform for the functional investigation of membrane proteins in giant unilamellar vesicles.Soft matter · 2022Article
- Shape Deformation, Budding and Division of Giant Vesicles and Artificial Cells: A Review.Life (Basel, Switzerland) · 2022Review
- Rapid and Facile Preparation of Giant Vesicles by the Droplet Transfer Method for Artificial Cell Construction.Frontiers in bioengineering and biotechnology · 2022Article
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Authors and funding
7 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Photosynthesis is responsible for the photochemical conversion of light into the chemical energy that fuels the planet Earth. The photochemical core of this process in all photosynthetic organisms is a transmembrane protein called the reaction center. In purple photosynthetic bacteria a simple version of this photoenzyme catalyzes the reduction of a quinone molecule, accompanied by the uptake of two protons from the cytoplasm. This results in the establishment of a proton concentration gradient across the lipid membrane, which can be ultimately harnessed to synthesize ATP. Herein we show that synthetic protocells, based on giant lipid vesicles embedding an oriented population of reaction centers, are capable of generating a photoinduced proton gradient across the membrane. Under continuous illumination, the protocells generate a gradient of 0.061 pH units per min, equivalent to a proton motive force of 3.6 mV⋅min
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.