Evidence map›Paper›PMID 28320873›Full record

ArticleMolecular and cellular biology2017

Janet Y Leung, Harper L Wilson, Kristin J Voltzke, Lindsay A Williams, Hyo Jin Lee, Sara E Wobker, William Y Kim

Open access · bronzeAbstract read
In one paragraph

Article in Molecular and cellular biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 34 citations in OpenAlex.

  1. Targeting YAP1-Mediated Tubular Cell Senescence to Attenuate Maladaptive Repair and Fibrotic Transition After Acute Kidney Injury.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Cellular senescence and kidney aging.Clinical science (London, England : 1979) · 2023
    Review
  7. Review
  8. Article
  9. Review
  10. Article
  11. Review
  12. Review
  13. Article
  14. You Say You Want a Resolution (of Fibrosis).American journal of respiratory cell and molecular biology · 2020
    Review
  15. Tubule-Specific Mst1/2 Deficiency Induces CKDJournal of the American Society of Nephrology : JASN · 2020
    Article
  16. The emerging role of cellular senescence in renal diseases.Journal of cellular and molecular medicine · 2020
    Review
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Janet Y LeungLineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA janet_leung@med.unc.edu wykim@med.unc.edu.
Harper L WilsonLineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Kristin J VoltzkeLineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Lindsay A WilliamsLineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Hyo Jin LeeDepartment of Internal Medicine, Chungnam National University School of Medicine, Daejeon, Republic of Korea.
Sara E WobkerDepartment of Pathology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
William Y KimLineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA janet_leung@med.unc.edu wykim@med.unc.edu.
University of North Carolina at Chapel Hill · USChungnam National University · KR

Funding

Tissue Procurement & PathologyP50CA058223 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI KATHERINE A. HOADLEY · 1992 to 2026
$59.3M
NCI NIH HHS P50 CA058223
6 · The paper itself

Abstract

Tubulointerstitial fibrosis (TIF) is recognized as a final phenotypic manifestation in the transition from chronic kidney disease (CKD) to end-stage renal disease (ESRD). Here we show that conditional inactivation of

Indexed as

Cellular SenescenceAcute Kidney InjuryAdaptor Proteins, Signal TransducingAnimalsAristolochic AcidsCell Cycle ProteinsCollagenFibrosisGene DeletionGene Expression RegulationKidney DiseasesKidney TubulesMice, KnockoutPhenotypePhosphoproteinsPorphyrinsAdaptor Proteins, Signal Transducingaristolochic acid IAristolochic AcidsCell Cycle ProteinsCollagenPhosphoproteinsPorphyrinsSav1 protein, mouseSTAT3 Transcription FactorVerteporfinYap1 protein, mouseYAP-Signaling Proteinsfibrosismouserenalsenescence

Identifiers

PMID28320873
PMCPMC5452723
OpenAlexW2602593172

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.