Evidence map›Paper›PMID 28320749›Full record

ArticleJournal of the American Heart Association2017

Sex Differences in Percutaneous Coronary Intervention-Insights From the Coronary Angiography and PCI Registry of the German Society of Cardiology.

Tobias Heer, Matthias Hochadel, Karin Schmidt, Julinda Mehilli, Ralf Zahn, Karl-Heinz Kuck, Christian Hamm, Michael Böhm, Georg Ertl, Hans Martin Hoffmeister and 5 more

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 64 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
64citing papers in PubMed, 4 pooled it
7.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

64 citing papers in PubMed, 4 syntheses or guidelines pooled it, 133 citations in OpenAlex.

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  17. Italian Association of Hospital Cardiologists Position Paper 'Gender discrepancy: time to implement gender-based clinical management'.European heart journal supplements : journal of the European Society of Cardiology · 2024
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4 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

15 authors at 9 institutions in 1 country.

Tobias HeerKlinikum München Schwabing, Academic Teaching Hospital, University of Munich, Germany tobias.heer@klinikum-muenchen.de.
Matthias HochadelStiftung Institut für Herzinfarktforschung Ludwigshafen, Ludwigshafen, Germany.
Karin SchmidtMedizinische Klinik B, Klinikum der Stadt Ludwigshafen, Ludwigshafen, Germany.
Julinda MehilliMedizinische Klinik I, Klinikum der Ludwig-Maximilians-Universität München, Munich, Germany.
Ralf ZahnMedizinische Klinik B, Klinikum der Stadt Ludwigshafen, Ludwigshafen, Germany.
Karl-Heinz KuckAsklepios Klinik St. Georg Hamburg, Hamburg, Germany.
Christian HammKerckhoff Klinik Bad Nauheim, Bad Nauheim, Germany.
Michael BöhmUniversitätsklinikum des Saarlandes, Homburg/Saar, Germany.
Georg ErtlMedizinische Klinik und Poliklinik I/Comprehensive Heart Failure Center, Universitätsklinikum Würzburg, Würzburg, Germany.
Hans Martin HoffmeisterStädtisches Klinikum Solingen, Solingen, Germany.
Stefan SackKlinikum München Schwabing, Academic Teaching Hospital, University of Munich, Germany.
Jochen SengesStiftung Institut für Herzinfarktforschung Ludwigshafen, Ludwigshafen, Germany.
Steffen MassbergMedizinische Klinik I, Klinikum der Ludwig-Maximilians-Universität München, Munich, Germany.
Anselm K GittStiftung Institut für Herzinfarktforschung Ludwigshafen, Ludwigshafen, Germany.
Uwe ZeymerStiftung Institut für Herzinfarktforschung Ludwigshafen, Ludwigshafen, Germany.
Klinikum Ludwigshafen · DELudwig-Maximilians-Universität München · DEMünchen Klinik Schwabing · DEStiftung Institut für Herzinfarktforschung · DEAsklepios Klinik St. Georg · DEKerckhoff Klinik · DEStädtisches Klinikum Solingen · DEUniversitätsklinikum des Saarlandes · DEUniversitätsklinikum Würzburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSeveral studies have suggested sex-related differences in diagnostic and invasive therapeutic coronary procedures. METHODS AND

resultsData from consecutive patients who were enrolled in the Coronary Angiography and PCI Registry of the German Society of Cardiology were analyzed. We aimed to compare sex-related differences in in-hospital outcomes of patients undergoing percutaneous coronary intervention (PCI) for stable coronary artery disease, non-ST elevation acute coronary syndromes, ST elevation myocardial infarction, and cardiogenic shock. From 2007 until the end of 2009 data from 185 312 PCIs were prospectively registered: 27.9% of the PCIs were performed in women. Primary PCI success rate was identical between the sexes (94%). There were no sex-related differences in hospital mortality among patients undergoing PCI for stable coronary artery disease, non-ST elevation acute coronary syndromes, or cardiogenic shock except among ST elevation myocardial infarction patients. Compared to men, women undergoing primary PCI for ST elevation myocardial infarction have a higher risk of in-hospital death, age-adjusted odds ratio (1.19, 95% CI 1.06-1.33), and risk of ischemic cardiac and cerebrovascular events (death, myocardial infarction, transient ischemic attack/stroke), (age-adjusted odds ratio 1.19, 95% CI 1.16-1.29). Furthermore, access-related complications were twice as high in women, irrespective of the indication.

conclusionsDespite identical technical success rates of PCI between the 2 sexes, women with PCI for ST elevation myocardial infarction have a 20% higher age-adjusted risk of death and of ischemic cardiac and cerebrovascular events. Further research is needed to determine the reasons for these differences.

Indexed as

RegistriesAcute Coronary SyndromeAgedAge FactorsCardiologyCoronary AngiographyCoronary Artery DiseaseFemaleGermanyHospital MortalityHumansMaleMiddle AgedNon-ST Elevated Myocardial InfarctionOdds RatioPercutaneous Coronary Interventionacute coronary syndromeangioplasty and stentingcoronary artery diseaseoutcomewomen

Identifiers

PMID28320749
PMCPMC5524024
OpenAlexW2601090495

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.