Evidence map›Paper›PMID 28320746›Full record

ArticleJournal of the American Heart Association2017

Race and Sex Differences in QRS Interval and Associated Outcome Among Patients with Left Ventricular Systolic Dysfunction.

Tiffany C Randolph, Samuel Broderick, Linda K Shaw, Karen Chiswell, Robert J Mentz, Valentina Kutyifa, Eric J Velazquez, Francis R Gilliam, Kevin L Thomas

Abstract read
In one paragraph

Article in Journal of the American Heart Association, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Guideline
  2. Article
  3. Article
  4. A Review of Racial Differences and Disparities in ECG.International journal of environmental research and public health · 2025
    Review
  5. Article
  6. Article
  7. Electrocardiographic QRS duration is influenced by body mass index and sex.International journal of cardiology. Heart & vasculature · 2021
    Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Tiffany C RandolphDuke Clinical Research Institute, Durham, NC tiffany.randolph@conehealth.com.
Samuel BroderickDuke Clinical Research Institute, Durham, NC.
Linda K ShawDuke Clinical Research Institute, Durham, NC.
Karen ChiswellDuke Clinical Research Institute, Durham, NC.
Robert J MentzDuke Clinical Research Institute, Durham, NC.
Valentina KutyifaUniversity of Rochester Medical Center, Rochester, NY.
Eric J VelazquezDepartment of Medicine, Duke University School of Medicine, Durham, NC.
Francis R GilliamUniversity of North Carolina at Chapel Hill, NC.
Kevin L ThomasDuke Clinical Research Institute, Durham, NC.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundProlonged QRS duration is associated with increased mortality among heart failure patients, but race or sex differences in QRS duration and associated effect on outcomes are unknown. METHODS AND

resultsWe investigated QRS duration and morphology among 2463 black and white patients with heart failure and left ventricular ejection fraction ≤35% who underwent coronary angiography and 12-lead electrocardiography at Duke University Hospital from 1995 through 2011. We used multivariable Cox regression models to assess the relationship between QRS duration and all-cause mortality and investigate race-QRS and sex-QRS duration interaction. Median QRS duration was 105 ms (interquartile range [IQR], 92-132) with variation by race and sex (

conclusionsBlack individuals with heart failure had a shorter QRS duration and more often had non-left bundle branch block morphology than white patients. Women had left bundle branch block more commonly than men. Among black patients, modest QRS prolongation was associated with increased mortality.

Indexed as

Black or African AmericanWhite PeopleAgedBundle-Branch BlockCause of DeathCohort StudiesElectrocardiographyEthnicityFemaleHeart FailureHumansMaleMiddle AgedMortalityMultivariate AnalysisProportional Hazards Modelsheart failuremortalityQRSracesex

Identifiers

PMID28320746
PMCPMC5523998

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.