And Akt-ion! IQGAP1 in control of signaling pathways.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

14 citing papers in PubMed, 23 citations in OpenAlex.

1. miR-124 Ameliorates Spatial Memory Deficits in Rats Exposed to Single-Prolonged Stress by Downregulating IQGAP1 to Regulate Actin-Binding Proteins and Apoptosis in Hippocampal Neurons.Molecular neurobiology · 2026
   Article
2. Unraveling the Impact of KRAS Accessory Proteins on Oncogenic Signaling Pathways.Cells · 2026
   Article
3. Phosphoinositide signalling in cell motility and adhesion.Nature cell biology · 2025
   Review
4. Rivaroxaban as a Protector of Oxidative Stress-Induced Vascular Endothelial Glycocalyx Damage via the IQGAP1/PAR1-2/PI3K/Akt Pathway.Journal of vascular research · 2025
   Article
5. Role of scaffold proteins in the heterogeneity of glioblastoma.Cell communication and signaling : CCS · 2024
   Review
6. Differential expression of host oncogenes in human papillomavirus-associated nasopharyngeal and cervical epithelial cancers.The Kaohsiung journal of medical sciences · 2024
   Article
7. IQGAP1 scaffolding links phosphoinositide kinases to cytoskeletal reorganization.Biophysical journal · 2022
   Article
8. IPO5 Mediates EMT and Promotes Esophageal Cancer Development through the RAS-ERK Pathway.Oxidative medicine and cellular longevity · 2022
   Article
9. RAS Mediates BET Inhibitor-Endued Repression of Lymphoma Migration and Prognosticates a Novel Proteomics-Based Subgroup of DLBCL through Its Negative Regulator IQGAP3.Cancers · 2021
   Article
10. IQGAP1 activates PLC-δ1 by direct binding and moving along microtubule with DLC-1 to cell surface.FASEB bioAdvances · 2019
    Article
11. The Specificity of EGF-Stimulated IQGAP1 Scaffold Towards the PI3K-Akt Pathway is Defined by the IQ3 motif.Scientific reports · 2019
    Article
12. Oncogenic Ras Isoforms Signaling Specificity at the Membrane.Cancer research · 2018
    Review
13. IQ Domain-Containing GTPase-Activating Protein 1 Regulates Cytoskeletal Reorganization and Facilitates NKG2D-Mediated Mechanistic Target of Rapamycin Complex 1 Activation and Cytokine Gene Translation in Natural Killer Cells.Frontiers in immunology · 2018
    Article
14. The Expression of Key Guidance Genes at a Forebrain Axon Turning Point Is Maintained by Distinct Fgfr Isoforms but a Common Downstream Signal Transduction Mechanism.eNeuro
    Article

Corrections and comments

• Comment on
  AKT-phosphorylated FOXO1 suppresses ERK activation and chemoresistance by disrupting IQGAP1-MAPK interaction.2017

Authors and funding

2 authors at 1 institution in 1 country.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

Indexed as