Evidence map›Paper›PMID 28320639›Full record

ArticleInternational journal of hygiene and environmental health2017

Exposure to polycyclic aromatic hydrocarbons and volatile organic compounds among recently pregnant rural Guatemalan women cooking and heating with solid fuels.

John R Weinstein, Renée Asteria-Peñaloza, Anaité Diaz-Artiga, Gilberto Davila, S Katharine Hammond, Ian T Ryde, Joel N Meyer, Neal Benowitz, Lisa M Thompson

Abstract read
In one paragraph

Article in International journal of hygiene and environmental health, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 69 citations in OpenAlex.

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  13. Uncovering Evidence: Associations between Environmental Contaminants and Disparities in Women's Health.International journal of environmental research and public health · 2022
    Review
  14. Article
  15. In Vitro and In Vivo Experimental Studies of PMInternational journal of environmental research and public health · 2018
    Review
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  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

John R WeinsteinSchool of Nursing, University of California, San Francisco, 2 Koret Way, Box 0606, CA 94143-0606, USA.
Renée Asteria-PeñalozaSchool of Nursing, University of California, San Francisco, 2 Koret Way, Box 0606, CA 94143-0606, USA.
Anaité Diaz-ArtigaCentro de Estudios en Salud, Universidad del Valle, Guatemala City, Guatemala.
Gilberto DavilaCentro de Estudios en Salud, Universidad del Valle, Guatemala City, Guatemala.
S Katharine HammondEnvironmental Health Sciences, School of Public Health, University of California, Berkeley, Berkeley, California, USA.
Ian T RydeNicholas School of the Environment, Duke University, Durham, NC, USA.
Joel N MeyerNicholas School of the Environment, Duke University, Durham, NC, USA.
Neal BenowitzDivision of Clinical Pharmacology, Departments of Medicine and Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, CA, USA.
Lisa M ThompsonSchool of Nursing, University of California, San Francisco, 2 Koret Way, Box 0606, CA 94143-0606, USA. Electronic address: lisa.thompson@ucsf.edu.
University of California, San Francisco · USDuke University · USUniversidad del Valle de Guatemala · GTUniversity of California, Berkeley · US

Funding

CTSA: K12 COMPONENTKL2RR024130 · NCRR · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI JOHNSTON, S. CLAIBORNE · 2006 to 2011
$19.3M
Research Support CoreP30DA012393 · NIDA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI JACOB, PEYTON · 1999 to 2024
$17.1M
Liquid Chromatograph-Triple Quadrupole Mass SpectrometerS10RR026437 · NCRR · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI JACOB, PEYTON · 2010 to 2010
$448k
Prenatal household air pollution exposure: gas stove and behavioral interventionsR21ES025032 · NIEHS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI THOMPSON, LISA MARIE · 2015 to 2016
$376k
NCRR NIH HHS KL2 RR024130NCRR NIH HHS S10 RR026437NIDA NIH HHS P30 DA012393NIEHS NIH HHS R21 ES025032
6 · The paper itself

Abstract

backgroundHousehold air pollution is a major contributor to death and disability worldwide. Over 95% of rural Guatemalan households use woodstoves for cooking or heating. Woodsmoke contains carcinogenic or fetotoxic polycyclic aromatic hydrocarbons (PAHs) and volatile organic compounds (VOCs). Increased PAHs and VOCs have been shown to increase levels of oxidative stress.

objectiveWe examined PAH and VOC exposures among recently pregnant rural Guatemalan women exposed to woodsmoke and compared exposures to levels seen occupationally or among smokers.

methodsUrine was collected from 23 women who were 3 months post-partum three times over 72h: morning (fasting), after lunch, and following dinner or use of wood-fired traditional sauna baths (samples=68). Creatinine-adjusted urinary concentrations of metabolites of four PAHs and eight VOCs were analyzed by liquid chromatography-mass spectrometry. Creatinine-adjusted urinary biomarkers of oxidative stress, 8-isoprostane and 8-OHdG, were analyzed using enzyme-linked immunosorbent assays (ELISA). Long-term (pregnancy through 3 months prenatal) exposure to particulate matter and airborne PAHs were measured.

resultsWomen using wood-fueled chimney stoves are exposed to high levels of particulate matter (median 48h PM

conclusionsThe high concentrations of urinary PAH and VOC metabolites among recently pregnant women is alarming given the detrimental fetal and neonatal effects of prenatal PAH exposure. As most women used chimney woodstoves, cleaner fuels are critically needed to reduce smoke exposure.

Indexed as

AdultAir PollutantsAir Pollution, IndoorCookingEnvironmental MonitoringFemaleGuatemalaHeatingHumansParticulate MatterPolycyclic Aromatic HydrocarbonsPregnancyPyrenesRural PopulationSmokeVolatile Organic Compounds1-hydroxypyreneAir PollutantsParticulate MatterPolycyclic Aromatic HydrocarbonsPyrenesSmokeVolatile Organic CompoundsHousehold air pollutionPolycyclic aromatic hydrocarbonsSolid fuel useUrinary biomarkersVolatile organic compounds

Identifiers

PMID28320639
PMCPMC5474125
OpenAlexW2592275838

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.