Evidence map›Paper›PMID 28320387›Full record

ArticleBMC nephrology2017

Case report - atypical hemolytic uremic syndrome triggered by influenza B.

Robin Kobbe, Raphael Schild, Martin Christner, Jun Oh, Sebastian Loos, Markus J Kemper

Open access · goldAbstract readCase Reports
In one paragraph

Article in BMC nephrology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Atypical Hemolytic Uremic Syndrome after SARS-CoV-2 Infection: Report of Two Cases.International journal of environmental research and public health · 2022
    Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Influenza-associated thrombotic microangiopathies.Pediatric nephrology (Berlin, Germany) · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Robin KobbeUniversity Medical Center Hamburg-Eppendorf, Martinistr. 52, D-20246, Hamburg, Germany. r.kobbe@uke.de.
Raphael SchildUniversity Medical Center Hamburg-Eppendorf, Martinistr. 52, D-20246, Hamburg, Germany.
Martin ChristnerUniversity Medical Center Hamburg-Eppendorf, Martinistr. 52, D-20246, Hamburg, Germany.
Jun OhUniversity Medical Center Hamburg-Eppendorf, Martinistr. 52, D-20246, Hamburg, Germany.
Sebastian LoosUniversity Medical Center Hamburg-Eppendorf, Martinistr. 52, D-20246, Hamburg, Germany.
Markus J KemperUniversity Medical Center Hamburg-Eppendorf, Martinistr. 52, D-20246, Hamburg, Germany.
University Medical Center Hamburg-Eppendorf · DEUniversität Hamburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundInfluenza A infections have been described to cause secondary hemolytic uremic syndrome and to trigger atypical hemolytic uremic syndrome (aHUS) in individuals with an underlying genetic complement dysregulation. To date, influenza B has not been reported to trigger aHUS. CASE PRESENTATION: A 6-month-old boy presented with hemolytic uremic syndrome triggered by influenza B infection. Initially the child recovered spontaneously. When he relapsed Eculizumab treatment was initiated, resulting in complete and sustained remission. A pathogenic mutation in membrane cofactor protein (MCP) was detected.

conclusionInfluenza B is a trigger for aHUS and might be underreported as such. Influenza vaccination may protect patients at risk.

Indexed as

Atypical Hemolytic Uremic SyndromeDiagnosis, DifferentialHumansInfantInfluenza B virusInfluenza, HumanMaleTreatment OutcomeaHUSAtypical HUSHemolytic uremic syndromeHUSInfluenzaInfluenza vaccinationQuadrivalent

Identifiers

PMID28320387
PMCPMC5358041
OpenAlexW2599533460

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.