ArticleBMC pediatrics2017
Slow progress in diarrhea case management in low and middle income countries: evidence from cross-sectional national surveys, 1985-2012.
Article in BMC pediatrics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.
- Barriers and facilitators to implementation of oral rehydration therapy in low- and middle-income countries: A systematic review.PloS one · 2021Pooled it
- Randomised feasibility study of an intestinal adsorbent in acute diarrhoea in The Gambia.BMJ paediatrics open · 2025Trial
- The cost-effectiveness of community health workers delivering free diarrhoea treatment: evidence from Uganda.Health policy and planning · 2022Trial
- The role of price and convenience in use of oral rehydration salts to treat child diarrhea: A cluster randomized trial in Uganda.PLoS medicine · 2019Trial
- Trends and burden of diarrhoeal diseases across India, 1990 - 2023: A systematic analysis from the global burden of disease study 2023.New microbes and new infections · 2026Article
- Know-do gaps in the clinical management of childhood illness: evidence from three countries in sub-Saharan Africa.BMC public health · 2025Observational
- Prevalence and factors associated with laboratory-confirmed cases of select enteric infections in three Ethiopian communities, 2018-2022.PLOS global public health · 2025Article
- Facility capacity and provider knowledge for cholera surveillance and diarrhoea case management in cholera hotspots in the Democratic Republic of Congo - a mixed-methods study.Global health action · 2024Article
- Quantifying the Cost ofOpen forum infectious diseases · 2024Article
- What drives poor quality of care for child diarrhea? Experimental evidence from India.Science (New York, N.Y.) · 2024Article
- Prevalence and predictors of diarrhea among children under five in Ghana.BMC public health · 2024Article
- Management of Diarrhea in Young Children in Sub-Saharan Africa: Adherence to World Health Organization Recommendations During the Global Enteric Multisite Study (2007-2011) and the Vaccine Impact of Diarrhea in Africa (VIDA) Study (2015-2018).Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2023Article
- Assessment of Determinants of Paediatric Diarrhoea Case Management Adherence in Pakistan.Life (Basel, Switzerland) · 2023Article
- Under-five mortality in the Democratic Republic of the Congo: secondary analyses of survey and conflict data by province.Bulletin of the World Health Organization · 2022Article
- The burden of diarrhea, etiologies, and risk factors in India from 1990 to 2019: evidence from the global burden of disease study.BMC public health · 2022Article
- Article
- Health-care seeking for childhood diseases by parental age in Western and Central Africa between 1995 and 2017: A descriptive analysis using DHS and MICS from 23 low- and middle-income countries.Journal of global health · 2021Observational
- Oral Rehydration Therapy Utilization and Associated Factors Among Children with Diarrhea in Debre Berhan, Ethiopia, 2020.Pediatric health, medicine and therapeutics · 2021Article
- A Half Century of Oral Rehydration Therapy in Childhood Gastroenteritis: Toward Increasing Uptake and Improving Coverage.Digestive diseases and sciences · 2020Article
- Principles and Practice of Oral Rehydration.Current gastroenterology reports · 2019Review
Corrections and comments
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Authors and funding
3 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDiarrhea remains to be a main cause of childhood mortality. Diarrhea case management indicators reflect the effectiveness of child survival interventions. We aimed to assess time trends and country-wise changes in diarrhea case management indicators among under-5 children in low-and-middle-income countries.
methodsWe analyzed aggregate data from Demographic and Health Surveys and Multiple Indicator Cluster Surveys done from 1986 to 2012 in low-and-middle-income countries. Two-week prevalence rates of diarrhea, caregiver's care seeking behavior and three case management indicators were analyzed. We assessed overall time trends across the countries using panel data analyses and country-level changes between two sequential surveys.
resultsOverall, yearly increase in case management indicators ranged from 1 · 3 to 2 · 5%. In the year 2012, <50% of the children were given correct treatment (received oral rehydration and increased fluids) for diarrhea. Annually, an estimated 300 to 350 million children were not given oral rehydration solutions, or recommended home fluids or 'increased fluids' and 304 million children not taken to a healthcare provider during an episode of diarrhea. Overall, care seeking for diarrhea, increased from pre-2000 to post-2000, i.e. from 35 to 45%; oral rehydration rates increased by about 7% but the rate of 'increased fluids' decreased by 14%. Country-level trends showed that care seeking had decreased in 15 countries but increased in 33 countries. Care seeking from a healthcare provider increased by ≥10% in about 23 countries. Oral rehydration rates had increased by ≥10% in 15 countries and in 30 countries oral rehydration rates increased by <10%.
conclusionsVery limited progress has been made in the case management of childhood diarrhea. A better understanding of caregiver's care seeking behavior and health care provider's case management practices is needed to improve diarrhea case management in low- and-middle-income countries.
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