Evidence map›Paper›PMID 28320231›Full record

ArticleThe journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians2018

Maternal healthy lifestyle during early pregnancy and offspring birthweight: differences by offspring sex.

Sylvia E Badon, Raymond S Miller, Chunfang Qiu, Tanya K Sorensen, Michelle A Williams, Daniel A Enquobahrie

Abstract read
In one paragraph

Article in The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sylvia E Badona Department of Epidemiology , University of Washington , Seattle , WA , USA.
Raymond S Millerb Center for Perinatal Studies , Swedish Medical Center , Seattle , WA , USA.
Chunfang Qiub Center for Perinatal Studies , Swedish Medical Center , Seattle , WA , USA.
Tanya K Sorensenb Center for Perinatal Studies , Swedish Medical Center , Seattle , WA , USA.
Michelle A Williamsc Department of Epidemiology , Harvard T.H. Chan School of Public Health , Boston , MA , USA.
Daniel A Enquobahriea Department of Epidemiology , University of Washington , Seattle , WA , USA.

Funding

The Epidemiology of Marine Fatty Acids and PreeclampsiaR01HD032562 · NICHD · SWEDISH MEDICAL CENTER, FIRST HILL · PI WILLIAMS, MICHELLE A. · 1996 to 2006
$3.0M
University of Washington Reproductive, Perinatal and Pediatric Epidemiology T32HD052462 · NICHD · UNIVERSITY OF WASHINGTON · PI HOLT, VICTORIA L · 2006 to 2017
$2.7M
Vitamin D related genes and developmental origins of cardiometabolic riskK01HL103174 · NHLBI · UNIVERSITY OF WASHINGTON · PI ENQUOBAHRIE, DANIEL ASMAMAW · 2010 to 2014
$661k
NHLBI NIH HHS K01 HL103174NICHD NIH HHS R01 HD032562NICHD NIH HHS T32 HD052462
6 · The paper itself

Abstract

purposeIndividual maternal lifestyle factors during pregnancy have been associated with offspring birthweight; however, associations of combined lifestyle factors with birthweight and potential differences by offspring sex have not been examined. MATERIALS AND

methodsParticipants (N = 2924) were identified from a pregnancy cohort in Washington state. Lifestyle factors during early pregnancy were dichotomized based on Alternate Healthy Eating Index score ≥62, leisure time physical activity (LTPA) ≥ 150 min/week, not smoking during pregnancy and Perceived Stress Scale score ≤3, then combined into a lifestyle score (0-4). Regression models were run overall and stratified by offspring sex, prepregnancy overweight/obese (BMI ≥25 kg/m

resultsOverall, 20% of participants had healthy diet, 95% were nonsmokers, 55% had low stress levels, and 66% were physically active. Lifestyle score was not associated with birthweight (β = 3.3 g; 95% CI: -14.5, 21.0); however, associations differed by offspring sex (p = .009). For each unit increase in lifestyle score, there was a suggested 22.4 g higher birthweight (95% CI: -2.7, 47.6) among males and 14.6 g lower birthweight (95% CI: -39.9, 10.7) among females. Prepregnancy BMI and LTPA did not modify associations.

conclusionsHealthy lifestyle score in early pregnancy may be associated with greater birthweight among male offspring, but lower birthweight among female offspring.

Indexed as

Maternal HealthSex FactorsAdultBirth WeightDietDiet, HealthyExerciseFemaleHealthy LifestyleHumansLeisure ActivitiesMalePregnancySmokingStress, PsychologicalBirthweightdietlifestylephysical activityphysiological stresspregnancysmoking

Identifiers

PMID28320231
PMCPMC6179147

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.