Evidence map›Paper›PMID 28319790›Full record

ReviewCurrent opinion in virology2017

Within host RNA virus persistence: mechanisms and consequences.

Richard E Randall, Diane E Griffin

Abstract readReview
In one paragraph

Review in Current opinion in virology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers.

0numbers the graph read from it
0cells of the map it votes in
63citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

63 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. High Risk of Heart Tumors after COVID-19.Life (Basel, Switzerland) · 2023
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Review
  17. Coronavirus disease 2019 and lung cancer: where are we?Exploration of targeted anti-tumor therapy · 2023
    Review
  18. Review
  19. Review
  20. Review

3 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Richard E RandallSchool of Biology, University of St. Andrews, Scotland, UK. Electronic address: rer@st-andrews.ac.uk.
Diane E GriffinW. Harry Feinstone Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.

Funding

CONTROL OF ALPHAVIRUS REPLICATION IN THE NERVOUS SYSTEMR01NS038932 · NINDS · JOHNS HOPKINS UNIVERSITY · PI GRIFFIN, DIANE E · 2001 to 2016
$4.9M
Role of CD4 T cells in fatal alphavisus encephalomyelitisR01NS087539 · NINDS · JOHNS HOPKINS UNIVERSITY · PI GRIFFIN, DIANE E · 2014 to 2018
$1.9M
NINDS NIH HHS R01 NS038932NINDS NIH HHS R01 NS087539Wellcome TrustWellcome Trust 101788/Z/13/Z
6 · The paper itself

Abstract

In a prototypical response to an acute viral infection it would be expected that the adaptive immune response would eliminate all virally infected cells within a few weeks of infection. However many (non-retrovirus) RNA viruses can establish 'within host' persistent infections that occasionally lead to chronic or reactivated disease. Despite the importance of 'within host' persistent RNA virus infections, much has still to be learnt about the molecular mechanisms by which RNA viruses establish persistent infections, why innate and adaptive immune responses fail to rapidly clear these infections, and the epidemiological and potential disease consequences of such infections.

Indexed as

Chronic DiseaseHost-Pathogen InteractionsVirus LatencyAnimalsHumansRNA Virus Infections

Identifiers

PMID28319790
PMCPMC5474179

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.