Evidence map›Paper›PMID 28319779›Full record

ReviewBiomaterials2017

Supramolecular biofunctional materials.

Jie Zhou, Jie Li, Xuewen Du, Bing Xu

Abstract readReview
In one paragraph

Review in Biomaterials, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

55 citing papers in PubMed.

  1. Article
  2. Review
  3. Reciprocity in dynamics of supramolecular biosystems for the clustering of ligands and receptors.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  4. Review
  5. Review
  6. Antioxidant Peptide-Based Nanocarriers for Delivering Wound Healing Agents.Tissue engineering and regenerative medicine · 2025
    Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. ACS biomaterials science & engineering · 2023
    Article
  13. Article
  14. Review
  15. Tailored Supramolecular Cage for Efficient Bio-Labeling.International journal of molecular sciences · 2023
    Article
  16. An Overview of Supramolecular Platforms Boosting Drug Delivery.Bioinorganic chemistry and applications · 2023
    Review
  17. Review
  18. Anion Effects on the Supramolecular Self-Assembly of Cationic Phenylalanine Derivatives.Langmuir : the ACS journal of surfaces and colloids · 2022
    Article
  19. Review
  20. Gels (Basel, Switzerland) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jie ZhouDepartment of Chemistry, Brandeis University, 415 South Street, Waltham, MA 02453, USA.
Jie LiDepartment of Chemistry, Brandeis University, 415 South Street, Waltham, MA 02453, USA.
Xuewen DuDepartment of Chemistry, Brandeis University, 415 South Street, Waltham, MA 02453, USA.
Bing XuDepartment of Chemistry, Brandeis University, 415 South Street, Waltham, MA 02453, USA. Electronic address: bxu@brandeis.edu.

Funding

Subcellular Enzyme-instructed self-assembly for molecular anticancer nanomedicinesR01CA142746 · NCI · BRANDEIS UNIVERSITY · PI Bing Xu · 2010 to 2026
$6.4M
Howard Hughes Medical InstituteNCI NIH HHS R01 CA142746
6 · The paper itself

Abstract

This review discusses supramolecular biofunctional materials, a novel class of biomaterials formed by small molecules that are held together via noncovalent interactions. The complexity of biology and relevant biomedical problems not only inspire, but also demand effective molecular design for functional materials. Supramolecular biofunctional materials offer (almost) unlimited possibilities and opportunities to address challenging biomedical problems. Rational molecular design of supramolecular biofunctional materials exploit powerful and versatile noncovalent interactions, which offer many advantages, such as responsiveness, reversibility, tunability, biomimicry, modularity, predictability, and, most importantly, adaptiveness. In this review, besides elaborating on the merits of supramolecular biofunctional materials (mainly in the form of hydrogels and/or nanoscale assemblies) resulting from noncovalent interactions, we also discuss the advantages of small peptides as a prevalent molecular platform to generate a wide range of supramolecular biofunctional materials for the applications in drug delivery, tissue engineering, immunology, cancer therapy, fluorescent imaging, and stem cell regulation. This review aims to provide a brief synopsis of recent achievements at the intersection of supramolecular chemistry and biomedical science in hope of contributing to the multidisciplinary research on supramolecular biofunctional materials for a wide range of applications. We envision that supramolecular biofunctional materials will contribute to the development of new therapies that will ultimately lead to a paradigm shift for developing next generation biomaterials for medicine.

Indexed as

Amino Acid SequenceAnimalsBiocompatible MaterialsDrug Delivery SystemsHumansHydrogelsModels, MolecularTissue EngineeringBiocompatible MaterialsHydrogelsApplicationsBiofunctionalHydrogelsMaterialsNoncovalent interactionSupramolecular

Identifiers

PMID28319779
PMCPMC5470592

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.