Evidence map›Paper›PMID 28319333›Full record

ReviewWiley interdisciplinary reviews. Developmental biology2017

The two domain hypothesis of limb prepattern and its relevance to congenital limb anomalies.

Hirotaka Tao, Yasuhiko Kawakami, Chi-Chung Hui, Sevan Hopyan

Abstract readReview
In one paragraph

Review in Wiley interdisciplinary reviews. Developmental biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Hirotaka TaoProgram in Developmental and Stem Cell Biology, Research Institute, The Hospital for Sick Children, Toronto, Canada.
Yasuhiko KawakamiDepartment of Genetics, Cell Biology and Development, Stem Cell Institute, University of Minnesota, Minneapolis, MN, USA.
Chi-Chung HuiProgram in Developmental and Stem Cell Biology, Research Institute, The Hospital for Sick Children, Toronto, Canada.
Sevan HopyanProgram in Developmental and Stem Cell Biology, Research Institute, The Hospital for Sick Children, Toronto, Canada.

Funding

Genetic Regulation of Progenitor Cells in Appendicular Skeletal DevelopmentR01AR064195 · NIAMS · UNIVERSITY OF MINNESOTA · PI KAWAKAMI, YASUHIKO · 2013 to 2022
$3.3M
CIHRNIAMS NIH HHS R01 AR064195
6 · The paper itself

Abstract

Functional annotation of mutations that cause human limb anomalies is enabled by basic developmental studies. In this study, we focus on the prepatterning stage of limb development and discuss a recent model that proposes anterior and posterior domains of the early limb bud generate two halves of the future skeleton. By comparing phenotypes in humans with those in model organisms, we evaluate whether this prepatterning concept helps to annotate human disease alleles. WIREs Dev Biol 2017, 6:e270. doi: 10.1002/wdev.270 For further resources related to this article, please visit the WIREs website.

Indexed as

Gene Expression Regulation, DevelopmentalAnimalsExtremitiesHumansLimb Deformities, Congenital

Identifiers

PMID28319333
PMCPMC5679199

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.