Evidence map›Paper›PMID 28319169›Full record

ArticlePloS one2017

High MELD score and extended operating time predict prolonged initial ICU stay after liver transplantation and influence the outcome.

Panagiota Stratigopoulou, Andreas Paul, Dieter P Hoyer, Stylianos Kykalos, Fuat H Saner, Georgios C Sotiropoulos

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Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

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16citing papers in PubMed
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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

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3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Panagiota StratigopoulouDepartment of General, Visceral and Transplantation Surgery University Hospital Essen, Essen, Germany.
Andreas PaulDepartment of General, Visceral and Transplantation Surgery University Hospital Essen, Essen, Germany.
Dieter P HoyerDepartment of General, Visceral and Transplantation Surgery University Hospital Essen, Essen, Germany.
Stylianos KykalosDepartment of General, Visceral and Transplantation Surgery University Hospital Essen, Essen, Germany.
Fuat H SanerDepartment of General, Visceral and Transplantation Surgery University Hospital Essen, Essen, Germany.
Georgios C SotiropoulosDepartment of General, Visceral and Transplantation Surgery University Hospital Essen, Essen, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe aim of the present study is to determine the incidence of a prolonged (>3 days) initial ICU-stay after liver transplantation (LT) and to identify risk factors for it. PATIENTS AND

methodsWe retrospectively analyzed data of adult recipients who underwent deceased donor first-LT at the University Hospital Essen between 11/2003 and 07/2012 and showed a primary graft function.

resultsOf the 374 recipients, 225 (60.16%) had prolonged ICU-stay. On univariate analysis, donor INR, high doses of vasopressors, "rescue-offer" grafts, being hospitalized at transplant, high urgency cases, labMELD, alcoholic cirrhosis, being on renal dialysis and length of surgery were associated with prolonged ICU-stay. After multivariate analysis, only the labMELD and the operation's length were independently correlated with prolonged ICU-stay. Cut-off values for these variables were 19 and 293.5 min, respectively. Hospital stay was longer for patients with a prolonged initial ICU-stay (p<0.001). Survival rates differed significantly between the two groups at 3 months, 1-year and 5-years after LT (p<0.001).

conclusionsLabMELD and duration of LT were identified as independent predictors for prolonged ICU-stay after LT. Identification of recipients in need of longer ICU-stay could contribute to a more evidenced-based and cost-effective use of ICU facilities in transplant centers.

Indexed as

Intensive Care UnitsLength of StayOperative TimeArea Under CurveEnd Stage Liver DiseaseFemaleGraft SurvivalHumansIncidenceKaplan-Meier EstimateLiver TransplantationLogistic ModelsMaleMiddle AgedPrognosisRetrospective Studies

Identifiers

PMID28319169
PMCPMC5358862

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