Observational studyJournal of diabetes and its complications2017
High rates of severe hypoglycemia among African American patients with diabetes: the surveillance, prevention, and Management of Diabetes Mellitus (SUPREME-DM) network.
Observational study in Journal of diabetes and its complications, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
30 citing papers in PubMed, 53 citations in OpenAlex.
- Severe Hypoglycemia and Incident Heart Failure Among Adults With Type 2 Diabetes.The Journal of clinical endocrinology and metabolism · 2022Trial
- Preventing Severe Hypoglycemia in Type 2 Diabetes: Randomized Controlled Trial of Proactive Care With Versus Without Psychoeducation.Journal of general internal medicine · 2026Article
- Real-world incidence and risk factors of level 3 (severe) hypoglycaemia in adults with type 1 or 2 diabetes (iNPHORM, United States).Diabetes, obesity & metabolism · 2026Article
- Overall Uptake and Racial, Ethnic, and Socioeconomic Disparities in the Use of Continuous Glucose Monitoring Devices Among Insulin-Treated Older Adults With Type 2 Diabetes.Diabetes care · 2025Article
- Ethnic disparities in HbA1c and hypoglycemia among youth with type 1 diabetes: beyond access to technology, social deprivation and mean blood glucose.BMJ open diabetes research & care · 2025Observational
- Non-Hispanic Black Individuals Have Higher Glucose-Adjusted HbA1c Levels and Risk for Severe Hypoglycemia: Evidence From the Diabetes Control and Complications Trial.Diabetes care · 2024Article
- Follow up care for adults with diabetes treated for severe hypoglycemia by emergency medical Services, 2013-2019.Diabetes research and clinical practice · 2024Article
- Second-Line Pharmaceutical Treatments for Patients with Type 2 Diabetes.JAMA network open · 2023Article
- Racial and Ethnic Differences in the Association Between Mean Glucose and Hemoglobin A1c.Diabetes technology & therapeutics · 2023Article
- Use of Real-World Data in Population Science to Improve the Prevention and Care of Diabetes-Related Outcomes.Diabetes care · 2023Review
- 6. Glycemic Targets: Standards of Care in Diabetes-2023.Diabetes care · 2023 · on this mapReview
- Advances in the management of type 2 diabetes in adults.BMJ medicine · 2023Review
- Association of Area-Level Socioeconomic Deprivation With Hypoglycemic and Hyperglycemic Crises in US Adults With Diabetes.JAMA network open · 2022Article
- Hypoglycemic and Hyperglycemic Crises Among U.S. Adults With Diabetes and End-stage Kidney Disease: Population-Based Study, 2013-2017.Diabetes care · 2022Article
- Hospital utilization for hypoglycemia among patients with type 2 diabetes using pooled data from six health systems.BMJ open diabetes research & care · 2021Article
- Second-Line Therapy for Type 2 Diabetes Management: The Treatment/Benefit Paradox of Cardiovascular and Kidney Comorbidities.Diabetes care · 2021Article
- Race and sex differences in the initiation of diabetes drugs by privately insured US adults.Endocrine · 2021Article
- Heart Disease and Stroke Statistics-2021 Update: A Report From the American Heart Association.Circulation · 2021Article
- Retinopathy develops at similar glucose levels but higher HbADiabetic medicine : a journal of the British Diabetic Association · 2020Article
- Racial differences in trends of serious hypoglycemia among higher risk older adults in US Veterans Health Administration, 2004-2015: Relationship to comorbid conditions, insulin use, and hemoglobin A1c level.Journal of diabetes and its complications · 2020Observational
Corrections and comments
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Authors and funding
16 authors at 7 institutions in 1 country.
Funding
Abstract
aimsSeven-year surveillance study (2005-2011) to evaluate race/ethnic differences in the trends in rates of severe hypoglycemia (SH) in a population of insured, at-risk adults with diabetes.
methodsSH events were identified via any primary or principal diagnosis from emergency department or inpatient encounters among African American, Asian, Latino and White adult diabetes patients treated with insulin or secretagogues (Sulfonylureas or Meglitinides), receiving care from integrated healthcare delivery systems across the United States. We calculated age- and sex-standardized annual SH rates and average annual percent change (AAPC) in SH rates.
resultsAnnual SH rates ranged from 1.8% to 2.1% during this 7-year observation period (2,200,471 person-years). African Americans had consistently higher SH rates compared with Whites, while Latinos and Asians had consistently lower rates compared with Whites in each of the 7 years (all p < 0.01). The trend increased significantly only among African Americans (AAPC = +4.3%; 95% CI: +2.1, +6.5%); in the other groups, the AAPC was not significantly different from zero.
conclusionsSurveillance efforts should monitor the racial/ethnic-specific rates. The factors underlying substantially higher rates of hypoglycemia in African Americans should be evaluated. Clinically and culturally-appropriate strategies to reduce the risk of SH need to be developed and tested.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.