Evidence map›Paper›PMID 28318385›Full record

ArticleCell cycle (Georgetown, Tex.)2017

Arsenic-induced sumoylation of Mus81 is involved in regulating genomic stability.

Liyan Hu, Feikun Yang, Lou Lu, Wei Dai

Open access · bronzeAbstract read
In one paragraph

Article in Cell cycle (Georgetown, Tex.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Review
  3. SUMO and the DNA damage response.Biochemical Society transactions · 2024
    Review
  4. Arsenic and cancer: Evidence and mechanisms.Advances in pharmacology (San Diego, Calif.) · 2023
    Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Review
  10. Article
  11. Review
  12. Arsenic and SUMO wrestling in protein modification.Cell cycle (Georgetown, Tex.) · 2017
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Liyan Hua Department of Environmental Medicine , New York University Langone Medical Center , Tuxedo , NY , USA.
Feikun Yangb University of Pennsylvania , Philadelphia , PA , USA.
Lou Luc Division of Molecular Medicine, Department of Medicine , David Geffen School of Medicine, University of California Los Angeles , Torrance , CA , USA.
Wei Daia Department of Environmental Medicine , New York University Langone Medical Center , Tuxedo , NY , USA.
NYU Langone Health · USUniversity of California, Los Angeles · USUniversity of Pennsylvania · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic environmental exposure to metal toxicants such as chromium and arsenic is closely related to the development of several types of common cancers. Genetic and epigenetic studies in the past decade reveal that post-translational modifications of histones play a role in metal carcinogenesis. However, exact molecular mechanisms of metal carcinogenesis remain to be elucidated. In this study we found that As

Indexed as

ArsenicCell Line, TumorChromosomes, HumanDNA-Binding ProteinsDNA DamageEndonucleasesGenomic InstabilityHEK293 CellsHumansLysineMitosisMolecular ChaperonesMutationProtein Inhibitors of Activated STATSumoylationUbiquitin-Protein LigasesArsenicDNA-Binding ProteinsEndonucleasesLysineMolecular ChaperonesMUS81 protein, humanPIAS3 protein, humanProtein Inhibitors of Activated STATUbiquitin-Protein LigasesarsenicchromiumDNA damage responseMus81sumoylation

Identifiers

PMID28318385
PMCPMC5405716
OpenAlexW2603770471

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.