Evidence map›Paper›PMID 28318006›Full record

ArticleMetallomics : integrated biometal science2017

Inhibiting the BfrB:Bfd interaction in Pseudomonas aeruginosa causes irreversible iron accumulation in bacterioferritin and iron deficiency in the bacterial cytosol.

Kate Eshelman, Huili Yao, Achala N D Punchi Hewage, Jacqueline J Deay, Josephine R Chandler, Mario Rivera

Open access · greenAbstract read
In one paragraph

Article in Metallomics : integrated biometal science, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 61 citations in OpenAlex.

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  13. Frontiers in molecular biosciences · 2024
    Article
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  18. International journal of molecular sciences · 2023
    Article
  19. Biomolecules · 2022
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Kate EshelmanDepartment of Chemistry and R. N. Adams Institute for Bioanalytical Chemistry, University of Kansas, Multidisciplinary Research Building, 2030 Becker Dr, Lawrence, KS 66047, USA. mrivera@ku.edu.
Huili Yao
Achala N D Punchi Hewage
Jacqueline J Deay
Josephine R Chandler
Mario Rivera
University of Kansas · US

Funding

Understanding the mechanobiology of stem cells in a microengineered 3D cardiac tissue environment with cardiomyopathyP20GM103638 · NIGMS · UNIVERSITY OF KANSAS LAWRENCE · PI HOLMSTROM, ERIK D · 2012 to 2021
$22.1M
Chemical tools for perturbing iron homeostasis in P. aeruginosaR01AI125529 · NIAID · UNIVERSITY OF KANSAS LAWRENCE · PI RIVERA, MARIO · 2016 to 2019
$1.4M
NIAID NIH HHS R01 AI125529NIGMS NIH HHS P20 GM103638
6 · The paper itself

Abstract

Iron is an essential nutrient for bacteria but the reactivity of Fe

Indexed as

Gene Expression Regulation, BacterialBacterial ProteinsCrystallography, X-RayCytochrome b GroupCytosolFerredoxinsFerritinsHomeostasisIronModels, MolecularMutationOxidation-ReductionProtein ConformationProtein Interaction Domains and MotifsPseudomonas aeruginosaBacterial ProteinsbacterioferritinCytochrome b GroupFerredoxinsFerritinsIron

Identifiers

PMID28318006
PMCPMC5494978
OpenAlexW2596753535

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.