ArticleScientific reports2017
NMR spectroscopy of single sub-nL ova with inductive ultra-compact single-chip probes.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
- In-cell NMR spectroscopy: advancements, applications, challenges, and future directions in structural biology.Magma (New York, N.Y.) · 2026Review
- Chemically Resolved Nuclear Magnetic Resonance Spectroscopy by Longitudinal Magnetization Detection with a Diamond Magnetometer.ACS measurement science au · 2026Article
- Live Metabolomics with NMR.Analytical chemistry · 2026Review
- Micro magnetic resonance spectroscopy for noninvasive metabolic screening of mammalian embryos and oocytes.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- 200 GHz single chip microsystems for dynamic nuclear polarization enhanced NMR spectroscopy.Nature communications · 2024Article
- Exploring the Potential of Broadband Complementary Metal Oxide Semiconductor Micro-Coil Nuclear Magnetic Resonance for Environmental Research.Molecules (Basel, Switzerland) · 2023Article
- Advances in nano- and microscale NMR spectroscopy using diamond quantum sensors.Chemical communications (Cambridge, England) · 2022Review
- A portable NMR platform with arbitrary phase control and temperature compensation.Magnetic resonance (Gottingen, Germany) · 2022Article
- NMR microsystem for label-free characterization of 3D nanoliter microtissues.Scientific reports · 2020Article
- Single-Chip Dynamic Nuclear Polarization Microsystem.Analytical chemistry · 2020Article
- A CMOS NMR needle for probing brain physiology with high spatial and temporal resolution.Nature methods · 2020Article
- Two-dimensional nuclear magnetic resonance spectroscopy with a microfluidic diamond quantum sensor.Science advances · 2019Article
- Blueprint for nanoscale NMR.Scientific reports · 2019Article
- In-Vivo NMR Spectroscopy: A Powerful and Complimentary Tool for Understanding Environmental Toxicity.Metabolites · 2018Review
- A Microfluidic Platform for Longitudinal Imaging in Caenorhabditis elegans.Journal of visualized experiments : JoVE · 2018Article
- Article
- 3D printed microchannels for sub-nL NMR spectroscopy.PloS one · 2018Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Nuclear magnetic resonance (NMR) spectroscopy enables non-invasive chemical studies of intact living matter. However, the use of NMR at the volume scale typical of microorganisms is hindered by sensitivity limitations, and experiments on single intact organisms have so far been limited to entities having volumes larger than 5 nL. Here we show NMR spectroscopy experiments conducted on single intact ova of 0.1 and 0.5 nL (i.e. 10 to 50 times smaller than previously achieved), thereby reaching the relevant volume scale where life development begins for a broad variety of organisms, humans included. Performing experiments with inductive ultra-compact (1 mm
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