Evidence map›Paper›PMID 28317679›Full record

ArticleJournal of cataract and refractive surgery2017

Distinguishing between contact lens warpage and ectasia: Usefulness of optical coherence tomography epithelial thickness mapping.

Julie M Schallhorn, Maolong Tang, Yan Li, Derek J Louie, Winston Chamberlain, David Huang

Erratum issuedAbstract read
In one paragraph

Article in Journal of cataract and refractive surgery, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Article
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  6. Review
  7. Article
  8. Article
  9. Article
  10. Observational
  11. Article
  12. Article
  13. Article
  14. Advanced epithelial mapping for refractive surgery.Indian journal of ophthalmology · 2020
    Review
  15. Article
  16. Biomechanical diagnostics of the cornea.Eye and vision (London, England) · 2020
    Review
  17. Understanding Corneal Epithelial Thickness Mapping.Middle East African journal of ophthalmology
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Julie M SchallhornFrom the Department of Ophthalmology (Schallhorn) and the Francis I. Proctor Foundation (Schallhorn), University of San Francisco, San Francisco, California, and the Center for Ophthalmic Optics and Lasers (Tang, Li, Louie, Chamberlain, Huang), Casey Eye Institute, and Department of Ophthalmology, Oregon Health & Science University, Portland, Oregon, USA.
Maolong TangFrom the Department of Ophthalmology (Schallhorn) and the Francis I. Proctor Foundation (Schallhorn), University of San Francisco, San Francisco, California, and the Center for Ophthalmic Optics and Lasers (Tang, Li, Louie, Chamberlain, Huang), Casey Eye Institute, and Department of Ophthalmology, Oregon Health & Science University, Portland, Oregon, USA.
Yan LiFrom the Department of Ophthalmology (Schallhorn) and the Francis I. Proctor Foundation (Schallhorn), University of San Francisco, San Francisco, California, and the Center for Ophthalmic Optics and Lasers (Tang, Li, Louie, Chamberlain, Huang), Casey Eye Institute, and Department of Ophthalmology, Oregon Health & Science University, Portland, Oregon, USA.
Derek J LouieFrom the Department of Ophthalmology (Schallhorn) and the Francis I. Proctor Foundation (Schallhorn), University of San Francisco, San Francisco, California, and the Center for Ophthalmic Optics and Lasers (Tang, Li, Louie, Chamberlain, Huang), Casey Eye Institute, and Department of Ophthalmology, Oregon Health & Science University, Portland, Oregon, USA.
Winston ChamberlainFrom the Department of Ophthalmology (Schallhorn) and the Francis I. Proctor Foundation (Schallhorn), University of San Francisco, San Francisco, California, and the Center for Ophthalmic Optics and Lasers (Tang, Li, Louie, Chamberlain, Huang), Casey Eye Institute, and Department of Ophthalmology, Oregon Health & Science University, Portland, Oregon, USA.
David HuangFrom the Department of Ophthalmology (Schallhorn) and the Francis I. Proctor Foundation (Schallhorn), University of San Francisco, San Francisco, California, and the Center for Ophthalmic Optics and Lasers (Tang, Li, Louie, Chamberlain, Huang), Casey Eye Institute, and Department of Ophthalmology, Oregon Health & Science University, Portland, Oregon, USA. Electronic address: davidhuang@alum.mit.edu.

Funding

Proteomics CoreP30EY010572 · NEI · OREGON HEALTH & SCIENCE UNIVERSITY · PI TED S ACOTT · 1995 to 2026
$19.4M
Guiding the Treatment of Anterior Eye Disease with Optical Coherence TomographyR01EY018184 · NEI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI HUANG, DAVID · 2008 to 2015
$4.9M
NEI NIH HHS P30 EY010572NEI NIH HHS R01 EY018184
6 · The paper itself

Abstract

purposeTo distinguish between corneal ectasia and contact lens-related warpage by characteristic patterns on corneal topography and optical coherence tomography (OCT) epithelial thickness maps.

settingCasey Eye Institute, Portland, Oregon, USA.

designProspective and retrospective case series.

methodsAxial and mean power maps were obtained on corneal topography systems. Epithelial thickness maps were generated using RTVue OCT. A sector divider was applied to all maps. The locations of the minimum epithelial thickness, maximum epithelial thickness, maximum axial power, and maximum mean power were determined based on sector averages. Agreement was defined as the extremums occurring in the same or adjacent sectors.

resultsTwenty-one eyes with keratoconus, 6 eyes with forme fruste keratoconus (better eye of asymmetric keratoconus), and 15 eyes with contact lens-related warpage were identified. The keratoconus and forme fruste keratoconus eyes had coincident topographic steepening with epithelial thinning. The locations of minimum epithelial thickness and maximum axial power agreed in 90% of the keratoconic eyes, while the minimum epithelial thickness and maximum mean power agreed in 95% of them. Conversely, the warpage eyes had coincident topographic steepening with epithelial thickening and normal pachymetry maps. The locations of maximum epithelial thickness and maximum axial power agreed in 93% of the warpage eyes, while the maximum epithelial thickness and maximum mean power agreed in all warpage eyes.

conclusionResults show that epithelial thickness maps and corneal topographic maps are powerful synergistic tools in evaluating eyes with abnormal topography and can help differentiate between keratoconus and nonectatic conditions.

Indexed as

Corneal TopographyTomography, Optical CoherenceAdultContact LensesCorneal PachymetryDilatation, PathologicEpithelium, CornealFemaleFourier AnalysisHumansKeratoconusMaleProspective StudiesProsthesis FailureRetrospective StudiesROC Curve

Identifiers

PMID28317679
PMCPMC5362118

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.