ArticleBiological psychiatry2017
What's the Buzz About Hydroxynorketamine? Is It the History, the Story, the Debate, or the Promise?
Article in Biological psychiatry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed.
- Ketamine metabolism via hepatic CYP450 isoforms contributes to its sustained antidepressant actions.Neuropharmacology · 2024Article
- Reproducing the dopamine pathophysiology of schizophrenia and approaches to ameliorate it: a translational imaging study with ketamine.Molecular psychiatry · 2021Article
- Hydroxynorketamines: Pharmacology and Potential Therapeutic Applications.Pharmacological reviews · 2021Review
- (Proceedings of the National Academy of Sciences of the United States of America · 2019Article
- Lack of deuterium isotope effects in the antidepressant effects of (R)-ketamine in a chronic social defeat stress model.Psychopharmacology · 2018Article
- No Sex-Specific Differences in the Acute Antidepressant Actions of (R)-Ketamine in an Inflammation Model.The international journal of neuropsychopharmacology · 2018Article
- Sex differences in sub-anesthetic ketamine's antidepressant effects and abuse liability.Current opinion in behavioral sciences · 2018Article
- Ketamine and ketamine metabolites as novel estrogen receptor ligands: Induction of cytochrome P450 and AMPA glutamate receptor gene expression.Biochemical pharmacology · 2018Article
- Lack of metabolism in (R)-ketamine's antidepressant actions in a chronic social defeat stress model.Scientific reports · 2018Article
- Lack of Antidepressant Effects of (2R,6R)-Hydroxynorketamine in a Rat Learned Helplessness Model: Comparison with (R)-Ketamine.The international journal of neuropsychopharmacology · 2018Article
- BDNF at the synapse: why location matters.Molecular psychiatry · 2017Article
- Prefrontal Connectivity and Glutamate Transmission: Relevance to Depression Pathophysiology and Ketamine Treatment.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2017Article
- Ketamine, but Not the NMDAR Antagonist Lanicemine, Increases Prefrontal Global Connectivity in Depressed Patients.Chronic stress (Thousand Oaks, Calif.)Article
- Hydroxynorketamine: Implications for the NMDA Receptor Hypothesis of Ketamine's Antidepressant Action.Chronic stress (Thousand Oaks, Calif.)Article
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Authors and funding
1 author.
Funding
Abstract
PubMed holds no abstract for this paper.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.