Evidence map›Paper›PMID 28317511›Full record

Trial reportJournal of studies on alcohol and drugs2017

Randomized Study of Assessment Effects on Alcohol Use by Persons With HIV in Rural Uganda.

Nneka I Emenyonu, Robin Fatch, Winnie R Muyindike, Allen Kekibiina, Sarah Woolf-King, Judith A Hahn

Open access · bronzeAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of studies on alcohol and drugs, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Nneka I EmenyonuDepartment of Medicine, University of California, San Francisco, San Francisco, California, United States.
Robin FatchDepartment of Medicine, University of California, San Francisco, San Francisco, California, United States.
Winnie R MuyindikeFaculty of Medicine, Mbarara University of Science and Technology, Mbarara, Uganda.
Allen KekibiinaMbarara University of Science and Technology Grants Office, Mbarara, Uganda.
Sarah Woolf-KingDepartment of Medicine, University of California, San Francisco, San Francisco, California, United States.
Judith A HahnDepartment of Medicine, University of California, San Francisco, San Francisco, California, United States.
Syracuse University · USUniversity of California, San Francisco · USMbarara National Referral Hospital · UGMbarara University of Science and Technology · UG

Funding

Changes in Alcohol Consumption in HIV Positives in UgandaR01AA018631 · NIAAA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI HAHN, JUDITH ALISSA · 2010 to 2013
$2.0M
Training in Research Program on Alcohol Use by Persons with our at Risk for HIVK24AA022586 · NIAAA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI HAHN, JUDITH ALISSA · 2013 to 2023
$1.8M
Alcohol Use and High Risk Behavior Among HIV-Positive MenK01AA021671 · NIAAA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI WOOLF-KING, SARAH E · 2013 to 2017
$865k
NIAAA NIH HHS K01 AA021671NIAAA NIH HHS K24 AA022586NIAAA NIH HHS R01 AA018631
6 · The paper itself

Abstract

objectiveUnhealthy alcohol use is a crucial driver of HIV in sub-Saharan Africa, and interventions are needed. The goal of this study was to assess whether assessment itself (assessment reactivity) causes declines in alcohol use in a research study in persons with HIV in Uganda.

methodStudy participants were adult patients of the Immune Suppression Syndrome (ISS) Clinic in Mbarara, Uganda, who were new to HIV care and reported any alcohol consumption in the prior year. Participants were randomized to (a) a study cohort, with structured interviews, breath alcohol analysis tests, and blood draws conducted quarterly, or (b) a minimally assessed arm that engaged in these procedures only once, at 6 months after baseline. The main outcome was unhealthy drinking at 6 months, defined as Alcohol Use Disorders Identification Test-Consumption [AUDIT-C] positive (≥3 for women, ≥4 for men) or phosphatidylethanol (PEth; an alcohol biomarker) level ≥ 50 ng/ml. We also examined this outcome stratified by gender.

resultsWe examined 175 and 139 persons in the quarterly assessed versus minimally assessed arms, respectively. Overall, 54.8% were male, the median age was 30 (interquartile range: 25-36), and 58.0% initiated anti-retroviral therapy at 6 months. Nearly equal proportions (53.7% and 51.1% in the study quarterly assessed vs. minimally assessed arm, respectively) engaged in unhealthy drinking in the 3 months before the 6-month study visit (p = .64), and we found no evidence of interaction by gender (p = .36).

conclusionsWe found no evidence of assessment reactivity in a study that included quarterly study visits. Assessment is not sufficient to act as an intervention itself in this population with high levels of unhealthy drinking. Interventions are needed to decrease alcohol consumption in this population.

Indexed as

Rural PopulationAdultAlcohol DrinkingBiomarkersCohort StudiesFemaleGlycerophospholipidsHIV InfectionsHumansMaleUgandaYoung AdultBiomarkersGlycerophospholipidsphosphatidylethanol

Identifiers

PMID28317511
PMCPMC5554109
OpenAlexW2602489773

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.