Evidence map›Paper›PMID 28317282›Full record

ArticleCancer medicine2017

Cardiorespiratory fitness and risk of site-specific cancers: a long-term prospective cohort study.

Trude E Robsahm, Ragnhild S Falk, Trond Heir, Leiv Sandvik, Linda Vos, Jan Erikssen, Steinar Tretli

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancer medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 6 pooled it
6.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 6 syntheses or guidelines pooled it, 41 citations in OpenAlex.

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  20. Early-Life Cardiorespiratory Fitness and Long-term Risk of Prostate Cancer.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Trude E RobsahmDepartment of Research, Cancer Registry of Norway, PB 5313 Majorstuen, Oslo, 0304, Norway.ORCID http://orcid.org/0000-0002-1652-7734
Ragnhild S FalkOslo Centre for Biostatistics and Epidemiology, Oslo University Hospital, PB 4950 Nydalen, Oslo, 0424, Norway.
Trond HeirOslo Ischemia Study, Oslo University Hospital, Oslo, Norway.
Leiv SandvikOslo Centre for Biostatistics and Epidemiology, Oslo University Hospital, PB 4950 Nydalen, Oslo, 0424, Norway.
Linda VosDepartment of Research, Cancer Registry of Norway, PB 5313 Majorstuen, Oslo, 0304, Norway.
Jan ErikssenOslo Ischemia Study, Oslo University Hospital, Oslo, Norway.
Steinar TretliDepartment of Research, Cancer Registry of Norway, PB 5313 Majorstuen, Oslo, 0304, Norway.
Oslo University Hospital · NOCancer Registry of Norway · NONorwegian University of Science and Technology · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Based on self-reported physical activity, there is epidemiologic evidence for a beneficial relation between physical activity and colon cancer in men, but findings for other cancers are inconclusive. Measured cardiorespiratory fitness (CRF) can provide knowledge about the cancer-preventive value of physical activity. We aimed to assess relationships between CRF and risk of site-specific cancers. A cohort of 1997 healthy Norwegian men, aged 40-59 years at inclusion in 1972-1975, was followed for cancer throughout 2012 using data from the Cancer Registry of Norway. CRF was measured by a maximal exercise bicycle test at inclusion. Relationships between CRF and site-specific cancers were estimated using Cox regression, adjusted for age, body mass index, and smoking. During follow-up, 898 cancer cases were diagnosed in 758 men. When comparing men in CRF tertile 1 with men in tertiles 2 and 3, respectively, we found decreased risk of proximal colon cancer in tertile 2 (HR: 0.30, 95% CI: 0.13-0.73) and decreased risk of cancers of lung (0.39 95% CI: 0.22-0.66), pancreas (0.32 95% CI: 0.10-1.00), and bladder (HR: 0.40 95% CI: 0.21-0.74) in tertile 3. Furthermore, a significant trend for lower risk by increasing CRF tertile was found for cancers of proximal colon, lung, and bladder (P-value for trend <0.05). For other cancer sites, no significant association was found. Our results indicate that high midlife CRF may have cancer-preventive value.

Indexed as

AdultCardiorespiratory FitnessColonic NeoplasmsExercise TestHumansLung NeoplasmsMaleMiddle AgedNeoplasmsNorwayProspective StudiesRisk FactorsUrinary Bladder NeoplasmsCancer riskcardiorespiratory fitnessmeasurementprevention

Identifiers

PMID28317282
PMCPMC5387170
OpenAlexW2600182494

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.