ArticleHuman brain mapping2017
Cortical surface-based threshold-free cluster enhancement and cortexwise mediation.
Article in Human brain mapping, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Evaluation of thresholding methods for activation likelihood estimation meta-analysis via large-scale simulations.Human brain mapping · 2022Pooled it
- DMN function changes on resting state fMRI in perimenopausal women.Open medicine (Warsaw, Poland) · 2026Article
- Uncovering the neurological substrates underlying restlessness in cluster headache - A functional MRI study.The journal of headache and pain · 2025Article
- The Influence of Structural Brain Changes on Cognition in the Context of Healthy Aging: Exploring Mediation Effects Through gBAT-The Graphical Brain Association Tool.Human brain mapping · 2024Article
- Clustering the cortical laminae: in vivo parcellation.Brain structure & function · 2024Article
- VertexWiseR: A package for simplified vertex-wise analyses of whole-brain and hippocampal surfaces in R.Imaging neuroscience (Cambridge, Mass.) · 2024Article
- Residential green space and air pollution are associated with brain activation in a social-stress paradigm.Scientific reports · 2022Article
- The interaction of child abuse and rs1360780 of the FKBP5 gene is associated with amygdala resting-state functional connectivity in young adults.Human brain mapping · 2021Article
- Childhood socioeconomic status is prospectively associated with surface morphometry in adulthood.Developmental psychobiology · 2021Article
- Natural sleep loss is associated with lower mPFC activity during negative distracter processing.Cognitive, affective & behavioral neuroscience · 2021Article
- Cortical Surfaces Mediate the Relationship Between Polygenic Scores for Intelligence and General Intelligence.Cerebral cortex (New York, N.Y. : 1991) · 2020Article
- Differences in Neural Recovery From Acute Stress Between Cortisol Responders and Non-responders.Frontiers in psychiatry · 2018Article
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Authors and funding
16 authors.
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Abstract
Threshold-free cluster enhancement (TFCE) is a sensitive means to incorporate spatial neighborhood information in neuroimaging studies without using arbitrary thresholds. The majority of methods have applied TFCE to voxelwise data. The need to understand the relationship among multiple variables and imaging modalities has become critical. We propose a new method of applying TFCE to vertexwise statistical images as well as cortexwise (either voxel- or vertexwise) mediation analysis. Here we present TFCE_mediation, a toolbox that can be used for cortexwise multiple regression analysis with TFCE, and additionally cortexwise mediation using TFCE. The toolbox is open source and publicly available (https://github.com/trislett/TFCE_mediation). We validated TFCE_mediation in healthy controls from two independent multimodal neuroimaging samples (N = 199 and N = 183). We found a consistent structure-function relationship between surface area and the first independent component (IC1) of the N-back task, that white matter fractional anisotropy is strongly associated with IC1 N-back, and that our voxel-based results are essentially identical to FSL randomise using TFCE (all P
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