Evidence map›Paper›PMID 28317210›Full record

ArticleAddiction (Abingdon, England)2017

Epidemiology of HIV and hepatitis C infection among women who inject drugs in Northeast India: a respondent-driven sampling study.

Allison M McFall, Sunil S Solomon, Greg M Lucas, David D Celentano, Aylur K Srikrishnan, Muniratnam S Kumar, Shruti H Mehta

Open access · greenAbstract read
In one paragraph

Article in Addiction (Abingdon, England), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 3 pooled it
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 3 syntheses or guidelines pooled it, 19 citations in OpenAlex.

  1. Pooled it
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  11. Substance Use, Mental Health, HIV Testing, and Sexual Risk Behavior Among Men Who Have Sex With Men in the State of Maharashtra, India.AIDS education and prevention : official publication of the International Society for AIDS Education · 2018
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Allison M McFallJohns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.ORCID http://orcid.org/0000-0002-1157-2931
Sunil S SolomonJohns Hopkins University School of Medicine, Baltimore, MD, USA.
Greg M LucasJohns Hopkins University School of Medicine, Baltimore, MD, USA.
David D CelentanoJohns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Aylur K SrikrishnanYR Gaitonde Centre for AIDS Research and Education, Chennai, India.
Muniratnam S KumarYR Gaitonde Centre for AIDS Research and Education, Chennai, India.
Shruti H MehtaJohns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Johns Hopkins University · USYR Gaitonde Centre for AIDS Research and Education · IN

Funding

Vaccine Response and Immunotherapeutics SWGP30AI094189 · NIAID · JOHNS HOPKINS UNIVERSITY · PI Richard E. Chaisson · 2012 to 2026
$67.0M
Strategies to improve the HIV care continuum among key populations in IndiaR01DA041034 · NIDA · JOHNS HOPKINS UNIVERSITY · PI LUCAS, GREGORY M, MEHTA, SHRUTI H · 2015 to 2021
$6.7M
Integrated Care Clinics for IDUs in India: a cluster randomized trialR01DA032059 · NIDA · JOHNS HOPKINS UNIVERSITY · PI LUCAS, GREGORY M, MEHTA, SHRUTI H · 2011 to 2015
$6.3M
Johns Hopkins HIV Epidemiology and Prevention Sciences Training ProgramT32AI102623 · NIAID · JOHNS HOPKINS UNIVERSITY · PI Shruti H Mehta · 2013 to 2026
$5.3M
Treatment outcomes and comorbidity in HIV-infected IDUK24DA035684 · NIDA · JOHNS HOPKINS UNIVERSITY · PI LUCAS, GREGORY M · 2014 to 2024
$1.5M
NIAID NIH HHS P30 AI094189NIAID NIH HHS T32 AI102623NIDA NIH HHS K24 DA035684NIDA NIH HHS R01 DA032059NIDA NIH HHS R01 DA041034
6 · The paper itself

Abstract

BACKGROUND AND

aimsDespite extensive research on HIV and hepatitis C (HCV) among people who inject drugs (PWID), there remains a gap in knowledge on the burden among women who inject drugs and their unique contexts and risk factors. This analysis compares HIV and HCV prevalence in female and male PWID and estimates injection and sexual risk correlates of prevalent HIV and HCV infection among women in Northeast India.

designCross-sectional sample accrued using respondent-driven sampling.

settingSeven cities in Northeast India, 2013.

participantsA total of 6457 adult PWID. MEASUREMENTS: Participants completed an interviewer-administered survey. HIV infection was diagnosed on-site and HCV antibody testing was performed on stored specimens. HIV and HCV prevalence estimates were stratified by gender. Among women, the association of risk correlates with HIV and HCV were estimated using multi-level logistic regression models.

findingsA total of 796 (15.9%) of the PWID were women, of whom 52.9% [95% confidence interval (CI) = 49.3-56.5%] were HIV-infected and 22.3% (CI = 19.9-24.7%) were HCV-infected. HIV and HCV prevalence among men was 17.4% (CI = 16.9-24.7%) and 30.4% (CI = 31.2-32.0%), respectively. Among women, correlates of HIV were widowhood [adjusted odds ratio (aOR) versus currently married = 4.03, CI = 2.13-7.60] and a higher number of life-time sexual partners (aOR ≥8 versus none = 3.08, CI = 1.07-8.86). Correlates of HCV were longer injection duration (aOR per 10 years = 1.70, CI = 1.25-2.27), injecting only heroin and a combination of drugs (aOR versus pharmaceuticals only = 5.63, CI = 1.68-18.9 and aOR = 2.58, CI = 1.60-4.16, respectively), sharing needles/syringes (aOR = 2.46, CI = 1.29-4.56) and a larger PWID network (aOR ≥ 51 versus 1-5 = 4.17, CI = 2.43-7.17).

conclusionsWomen who inject drugs in Northeast India have a high HIV prevalence, which was more than double their hepatitis C (HCV) prevalence, an opposite pattern than is observed typically among male PWID. HIV infection is associated with sexual risk factors while injection-related behaviors appear to drive HCV infection.

Indexed as

AdultComorbidityCross-Sectional StudiesFemaleHepatitis CHIV InfectionsHumansIndiaPrevalenceRisk FactorsRisk-TakingSampling StudiesSubstance Abuse, IntravenousSurveys and QuestionnairesEpidemiologyhepatitis CHIVIndiaintravenous drug abuserespondent-driven samplingwomen

Identifiers

PMID28317210
PMCPMC5503783
OpenAlexW2604018390

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.