Evidence map›Paper›PMID 28316635›Full record

ReviewEvidence-based complementary and alternative medicine : eCAM2017

Epigenetic Mechanisms of Integrative Medicine.

Riya R Kanherkar, Susan E Stair, Naina Bhatia-Dey, Paul J Mills, Deepak Chopra, Antonei B Csoka

Registry-linked trialAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Evidence-based complementary and alternative medicine : eCAM, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06732934 (The Effect of Basic Body Awareness Therapy and Aerobic Exercise Approaches on Telomere Length in Young Individuals), which is not on this map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06732934 nacompletednot on this mapstarted 2023, after this paper: background citation

The Effect of Basic Body Awareness Therapy and Aerobic Exercise Approaches on Telomere Length in Young Individuals

TypeinterventionalSponsorSuleyman Demirel UniversityRan2023 to 2024Enrolled45ConditionsExerciseArmsexercise (Basic Body Awareness Therapy, exercise (aerobic exercise)
3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. Covid-19 and the Epigenetics of Learning.Postdigital science and education · 2021
    Article
  11. Article
  12. Article
  13. Observational
  14. Article
  15. Article
  16. Oxidative stress and male infertility.Nature reviews. Urology · 2017
    Review
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Riya R KanherkarEpigenetics Laboratory, Department of Anatomy, Howard University, 520 W St. NW, Washington, DC 20059, USA; Vision Genomics, LLC, 5725 North Capitol St. NE, Washington, DC 20011, USA.
Susan E StairVision Genomics, LLC, 5725 North Capitol St. NE, Washington, DC 20011, USA.
Naina Bhatia-DeyEpigenetics Laboratory, Department of Anatomy, Howard University, 520 W St. NW, Washington, DC 20059, USA.
Paul J MillsDepartment of Family Medicine and Public Health, University of California, San Diego, 9500 Gilman Drive-0628, San Diego, CA 92093, USA.
Deepak ChopraDepartment of Family Medicine and Public Health, University of California, San Diego, 9500 Gilman Drive-0628, San Diego, CA 92093, USA; The Chopra Foundation, 2013 Costa Del Mar, Carlsbad, CA 92009, USA.
Antonei B CsokaEpigenetics Laboratory, Department of Anatomy, Howard University, 520 W St. NW, Washington, DC 20059, USA; Vision Genomics, LLC, 5725 North Capitol St. NE, Washington, DC 20011, USA.ORCID 0000-0002-7287-5856

Funding

PROTEOMICS CORE FACILITYG12MD007597 · NIMHD · HOWARD UNIVERSITY · PI SOUTHERLAND, WILLIAM M. · 2012 to 2018
$14.8M
Advancing aging research through development of minority GerontologistsR25AG047843 · NIA · HOWARD UNIVERSITY · PI DUTTAROY, ATANU · 2014 to 2024
$3.3M
NIA NIH HHS R25 AG047843NIMHD NIH HHS G12 MD007597
6 · The paper itself

Abstract

Since time immemorial humans have utilized natural products and therapies for their healing properties. Even now, in the age of genomics and on the cusp of regenerative medicine, the use of complementary and alternative medicine (CAM) approaches represents a popular branch of health care. Furthermore, there is a trend towards a unified medical philosophy referred to as Integrative Medicine (IM) that represents the convergence of CAM and conventional medicine. The IM model not only considers the holistic perspective of the physiological components of the individual, but also includes psychological and mind-body aspects. Justification for and validation of such a whole-systems approach is in part dependent upon identification of the functional pathways governing healing, and new data is revealing relationships between therapies and biochemical effects that have long defied explanation. We review this data and propose a unifying theme: IM's ability to affect healing is due at least in part to epigenetic mechanisms. This hypothesis is based on a mounting body of evidence that demonstrates a correlation between the physical and mental effects of IM and modulation of gene expression and epigenetic state. Emphasis on mapping, deciphering, and optimizing these effects will facilitate therapeutic delivery and create further benefits.

Identifiers

PMID28316635
PMCPMC5339524

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.