Evidence map›Paper›PMID 28316613›Full record

ReviewPPAR research2017

PPAR Agonists for the Prevention and Treatment of Lung Cancer.

Sowmya P Lakshmi, Aravind T Reddy, Asoka Banno, Raju C Reddy

Open access · goldAbstract readReview
In one paragraph

Review in PPAR research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 55 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Review
  6. Diabetes Mellitus and Thyroid Cancers: Risky Correlation, Underlying Mechanisms and Clinical Prevention.Diabetes, metabolic syndrome and obesity : targets and therapy · 2024
    Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Biochemistry and biophysics reports · 2022
    Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Sowmya P LakshmiDepartment of Medicine, Division of Pulmonary, Allergy and Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA; Veterans Affairs Pittsburgh Healthcare System, Pittsburgh, PA 15240, USA.ORCID 0000-0003-1708-9462
Aravind T ReddyDepartment of Medicine, Division of Pulmonary, Allergy and Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA; Veterans Affairs Pittsburgh Healthcare System, Pittsburgh, PA 15240, USA.ORCID 0000-0001-8628-3467
Asoka BannoDepartment of Medicine, Division of Pulmonary, Allergy and Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA.
Raju C ReddyDepartment of Medicine, Division of Pulmonary, Allergy and Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA; Veterans Affairs Pittsburgh Healthcare System, Pittsburgh, PA 15240, USA.ORCID 0000-0001-5136-817X
University of Pittsburgh · US

Funding

PPAR-delta as a Novel Therapeutic Target in AsthmaR01AI125338 · NIAID · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI REDDY, RAJU C · 2016 to 2020
$2.2M
NIAID NIH HHS R01 AI125338
6 · The paper itself

Abstract

Lung cancer is the most common and most fatal of all malignancies worldwide. Furthermore, with more than half of all lung cancer patients presenting with distant metastases at the time of initial diagnosis, the overall prognosis for the disease is poor. There is thus a desperate need for new prevention and treatment strategies. Recently, a family of nuclear hormone receptors, the peroxisome proliferator-activated receptors (PPARs), has attracted significant attention for its role in various malignancies including lung cancer. Three PPARs, PPAR

Identifiers

PMID28316613
PMCPMC5337885
OpenAlexW2590764925

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.