Evidence map›Paper›PMID 28316508›Full record

ArticleStatistical modelling2016

Longitudinal Functional Models with Structured Penalties.

Madan G Kundu, Jaroslaw Harezlak, Timothy W Randolph

Abstract read
In one paragraph

Article in Statistical modelling, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Contrastive Latent Functional Model.Statistics in biosciences · 2026
    Article
  2. Article
  3. Article
  4. Article
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  7. Article
  8. Article
  9. Longitudinal dynamic functional regression.Journal of the Royal Statistical Society. Series C, Applied statistics · 2020
    Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Madan G KunduNovartis Pharmaceuticals Corporation (Oncology) East Hanover, NJ, USA.
Jaroslaw HarezlakDepartment of Biostatistics, Indiana University RM Fairbanks School of Public Health, IN, USA.
Timothy W RandolphBiostatistics and Biomathematics Program, Fred Hutchinson Cancer Research Center, WA, USA.

Funding

EDRN--DATA MANAGEMENT AND COORDINATING CENTERU01CA086368 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI FENG, ZIDING · 2000 to 2010
$16.9M
National NeuroAIDS Tissue Consortium Statistics and Data Coordinating CenterU01MH083545 · NIMH · INDIANA UNIVERSITY INDIANAPOLIS · PI YIANNOUTSOS, CONSTANTIN THEODORE · 2008 to 2012
$3.3M
Quantitative Methods for Spectral and Image Data in Proteomics ResearchR01CA126205 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI RANDOLPH, TIMOTHY W · 2006 to 2010
$1.3M
NCI NIH HHS R01 CA126205NCI NIH HHS U01 CA086368NIMH NIH HHS U01 MH083545
6 · The paper itself

Abstract

This article addresses estimation in regression models for longitudinally-collected functional covariates (time-varying predictor curves) with a longitudinal scaler outcome. The framework consists of estimating a time-varying coefficient function that is modeled as a linear combination of time-invariant functions with time-varying coefficients. The model uses extrinsic information to inform the structure of the penalty, while the estimation procedure exploits the equivalence between penalized least squares estimation and a linear mixed model representation. The process is empirically evaluated with several simulations and it is applied to analyze the neurocognitive impairment of HIV patients and its association with longitudinally-collected magnetic resonance spectroscopy (MRS) curves.

Indexed as

Functional data analysisgeneralized singular value decompositionlongitudinal dataLongPEER estimatestructured penalty

Identifiers

PMID28316508
PMCPMC5354471

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.