Evidence map›Paper›PMID 28316440›Full record

ArticleAsian journal of transfusion science

ABO incompatible renal transplant: Transfusion medicine perspective.

Raj Nath Makroo, Sweta Nayak, Mohit Chowdhry, Sanjiv Jasuja, Gaurav Sagar, N L Rosamma, Uday Kumar Thakur

Open access · diamondAbstract read
In one paragraph

Article in Asian journal of transfusion science. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Raj Nath MakrooDepartment of Transfusion Medicine and Immunohematology, Indraprastha Apollo Hospitals, New Delhi, India.
Sweta NayakDepartment of Transfusion Medicine and Immunohematology, Indraprastha Apollo Hospitals, New Delhi, India.
Mohit ChowdhryDepartment of Transfusion Medicine and Immunohematology, Indraprastha Apollo Hospitals, New Delhi, India.
Sanjiv JasujaDepartment of Nephrology, Indraprastha Apollo Hospitals, New Delhi, India.
Gaurav SagarDepartment of Nephrology, Indraprastha Apollo Hospitals, New Delhi, India.
N L RosammaDepartment of Transfusion Medicine and Immunohematology, Indraprastha Apollo Hospitals, New Delhi, India.
Uday Kumar ThakurDepartment of Transfusion Medicine and Immunohematology, Indraprastha Apollo Hospitals, New Delhi, India.
Indraprastha Apollo Hospitals · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionOur study presents an analysis of the trends of ABO antibody titers and the TPE (Therapeutic Plasma Exchange) procedures required pre and post ABO incompatible renal transplant. MATERIALS AND

methodsTwenty nine patients underwent ABO incompatible renal transplant during the study period. The ABO antibody titers were done using the tube technique and titer reported was the dilution at which 1+ reaction was observed. The baseline titers of anti-A and anti-B antibodies were determined. The titer targeted was ≤8. Patients were subjected to 1 plasma volume exchange with 5% albumin and 2 units of AB group FFP (Fresh Frozen Plasma) in each sitting. TPE procedures post-transplant were decided on the basis of rising antibody titer with/ without graft dysfunction.

resultsThe average number of TPE procedures required was 4-5 procedures/patient in the pretransplant and 2-3/patient in the post-transplant period. An average titer reduction of 1 serial dilution/procedure was noted for Anti-A and 1.1/procedure for Anti-B. Number of procedures required to reach the target titer was not significantly different for Anti-A and Anti-B (

conclusionWith an average of 4-5 TPE procedures pretransplant and 2-3 TPE procedures post transplants, ABO incompatible renal transplantations can be successfully accomplished.

Indexed as

ABO incompatiblerenaltherapeutic plasma exchangetiter

Identifiers

PMID28316440
PMCPMC5345280
OpenAlexW2591126541

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.