ArticleAsian journal of transfusion science
Antibody titers in Group O platelet donors.
Article in Asian journal of transfusion science. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 47 citations in OpenAlex.
- Analysis of Titers of Immunoglobulin M and Immunoglobulin G ABO Antibodies in Group O Blood and Plateletphersis Donors at a Tertiary Care Hospital.Annals of African medicine · 2026Article
- Cytokine Gene Polymorphisms Modulate Isohemagglutinin Titers and Classes: Another Aspect Towards the Link Between ABO Groups and Human Pathologies?International journal of molecular sciences · 2026Article
- Paper-based fluorescent assay for blood typing and antibody titer determination using long-term ambient-stored bioengineered RBCs.Nature communications · 2026Article
- Article
- Phenotype- and age-associated variations in non-specific agglutinins and complement components (C3 and C5a) in camels: Implications for transfusion compatibility and immune function.Veterinary world · 2025Article
- Article
- Association Between Blood Groups and COVID-19 CT Severity: A Retrospective Analysis From a Tertiary Care Center.Cureus · 2023Article
- Characteristics of ABO Antibodies in Group O Malaysian Blood Donors.The Malaysian journal of medical sciences : MJMS · 2023Article
- ABO blood group and COVID-19: a review on behalf of the ISBT COVID-19 Working Group.Vox sanguinis · 2021Review
- Efficacy of convalescent plasma according to blood groups in COVID-19 patientsTurkish journal of medical sciences · 2021Article
- Low Levels of Natural Anti-α-Frontiers in microbiology · 2021Article
- Convalescent Plasma Therapy for COVID-19: State of the Art.Clinical microbiology reviews · 2020Review
- Anti-A isohaemagglutinin titres and SARS-CoV-2 neutralization: implications for children and convalescent plasma selection.British journal of haematology · 2020Article
- Evaluation of immunoglobulin M and immunoglobulin G titers of ABO blood group system in blood donors at a blood center of a tertiary care hospital.Asian journal of transfusion scienceArticle
- ABO isoagglutinin titers in group "O" blood donors.Asian journal of transfusion scienceArticle
- Hemolysis in reverse grouping: Evaluation and implication of high titer isoagglutinin of two blood donors.Asian journal of transfusion scienceArticle
- A prospective observational study to evaluate effect of heat inactivation on ABO titers performed by column agglutination technology and conventional tube technique.Asian journal of transfusion scienceArticle
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
objectivesThe occurrence of hemolysis due to transfusion of ABO plasma-incompatible platelets (PLTs) is challenging. There has been no consensus for critical antibody titers in the transfusion community. This study was conducted to understand the trends of anti-A and anti-B antibody titer levels in O group donors and to identify any specific patterns of distribution in relation to age and gender. MATERIALS AND
methodsA total of 1635 Group O PLT donors were randomly selected for this prospective study. Serial 2-fold doubling dilutions were prepared for each sample to calculate the titer of anti-A and anti-B in a standard 96 well micro-plate. Tube technique was used for comparison with the microplate method for 100 samples.
resultsOut of 1635 donors, 1430 (87.46%) were males and 205 (12.54%) were females. The median titer for anti-A and anti-B was 128 with range from 4 to 2048. Spearman's correlation coefficient for microplate versus tube technique was estimated to be 0.803 (
conclusionMicroplate can be used to perform titers in resource-constrained settings. Screening for critical titers in O group donors is essential as they are more implicated in hemolytic transfusion reactions. In the absence of a global consensus on this topic, institutes may need to formulate their own guidelines on handling ABO plasma-incompatible PLT transfusions.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.