Evidence map›Paper›PMID 28316020›Full record

ArticleNeurochemical research2017

β-Hydroxybutyrate Boosts Mitochondrial and Neuronal Metabolism but is not Preferred Over Glucose Under Activated Conditions.

Lavanya B Achanta, Benjamin D Rowlands, Donald S Thomas, Gary D Housley, Caroline D Rae

Abstract read
PubMed Publisher
In one paragraph

Article in Neurochemical research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 42 citations in OpenAlex.

  1. Article
  2. Review
  3. Aspartate in the Brain: A Review.Neurochemical research · 2025
    Review
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Nutrition in the Neurocritical Care Unit: a New Frontier.Current treatment options in neurology · 2021
    Review
  15. Article
  16. Article
  17. Article
  18. Review
  19. Review
  20. How Can a Ketogenic Diet Improve Motor Function?Frontiers in molecular neuroscience · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Lavanya B AchantaNeuroscience Research Australia, Barker St, Randwick, NSW, 2031, Australia.
Benjamin D RowlandsNeuroscience Research Australia, Barker St, Randwick, NSW, 2031, Australia.
Donald S ThomasMark Wainwright Analytical Centre, UNSW Sydney, Sydney, NSW, 2052, Australia.
Gary D HousleyTranslational Neuroscience Facility, School of Medical Sciences, UNSW Sydney, Sydney, NSW, 2052, Australia.
Caroline D RaeNeuroscience Research Australia, Barker St, Randwick, NSW, 2031, Australia. c.rae@unsw.edu.au.
UNSW Sydney · AUNeuroscience Research Australia · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The ketone body, β-hydroxybutyrate (βOHB), is metabolised by the brain alongside the mandatory brain fuel glucose. To examine the extent and circumstances by which βOHB can supplement glucose metabolism, we studied guinea pig cortical brain slices using increasing concentrations of [U-

Indexed as

3-Hydroxybutyric AcidAnimalsDose-Response Relationship, DrugGlucoseGlutamineGuinea PigsMaleMitochondriaNeurons3-Hydroxybutyric AcidGlucoseGlutamineAcetate metabolismAstrocyte-neuronGlutamineKetone body metabolism

Identifiers

PMID28316020
OpenAlexW2596693353

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.