Trial reportBiogerontology2017
Changes in pro-inflammatory markers and leucine concentrations in response to Nordic Walking training combined with vitamin D supplementation in elderly women.
Trial report in Biogerontology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03417700 (Vitamin D as a Factor Modifying Adaptation to Diverse Forms of Exercise), which is not on this map. Cited by 27 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Vitamin D as a Factor Modifying Adaptation to Diverse Forms of Exercise
Who cites it
27 citing papers in PubMed, 1 synthesis or guideline pooled it, 52 citations in OpenAlex.
- Inflammatory Profile of Older Adults in Response to Physical Activity and Diet Supplementation: A Systematic Review.International journal of environmental research and public health · 2023Pooled it
- Investigation of the effectiveness Of 'Nordic Walking' training on geriatric individuals: a randomized comparative study.European geriatric medicine · 2026Trial
- Iron status determined changes in health measures induced by nordic walking with time-restricted eating in older adults- a randomised trial.BMC geriatrics · 2024Trial
- The Effect of Nordic Walking Training Combined with Vitamin D Supplementation on Postural Control and Muscle Strength in Elderly People-A Randomized Controlled Trial.International journal of environmental research and public health · 2018Trial
- The interplay between vitamin D status and exerkine signaling: implications for exercise adaptation in athletes: narrative review.Journal of the International Society of Sports Nutrition · 2026Review
- High mobility group box 1: DAMPening the danger molecule in cardiovascular disease with exercise.Cell stress & chaperones · 2026Review
- Enhanced gait following NW-RSA training links to reduced myostatin and improved L-arginine metabolites in older women with preserved vitamin D.Scientific reports · 2026Article
- Understanding the Role of Irisin in Longevity and Aging: A Narrative Review.Epidemiologia (Basel, Switzerland) · 2025Review
- Unlocking the potential of exercise: harnessing myokines to delay musculoskeletal aging and improve cognitive health.Frontiers in physiology · 2024Review
- Highlighting the idea of exerkines in the management of cancer patients with cachexia: novel insights and a critical review.BMC cancer · 2023Review
- Nordic Walking training in BungyPump form improves cognitive functions and physical performance and induces changes in amino acids and kynurenine profiles in older adults.Frontiers in endocrinology · 2023Article
- High-mobility group box 1 protein, receptor for advanced glycation end products and nucleosomes increases after marathon.Frontiers in physiology · 2023Article
- The Potential of Exerkines in Women's COVID-19: A New Idea for a Better and More Accurate Understanding of the Mechanisms behind Physical Exercise.International journal of environmental research and public health · 2022Review
- Letter to the editor Re: Faienza MF, Brunetti G, Grugni G, et al. The genetic background and vitamin D supplementation can affect irisin levels in Prader-Willi syndrome. J Endocrinol Invest 2021 Mar 3. https://doi.org/10.1007/s40618-021-01533-4.Journal of endocrinological investigation · 2022Article
- Impact of 12-Week Moderate-Intensity Aerobic Training on Inflammasome Complex Activation in Elderly Women.Frontiers in physiology · 2022Article
- Effects of Resistance Training Intervention along with Leucine-Enriched Whey Protein Supplementation on Sarcopenia and Frailty in Post-Hospitalized Older Adults: Preliminary Findings of a Randomized Controlled Trial.Journal of clinical medicine · 2021Article
- Article
- Article
- Irisin: A New Code Uncover the Relationship of Skeletal Muscle and Cardiovascular Health During Exercise.Frontiers in physiology · 2021Review
- Compound amino acid combined with high-dose vitamin B6 attenuate traumatic coagulopathy via inhibiting inflammation by HMGB1/TLR4/NF-κB pathway.Journal of inflammation (London, England) · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Mechanisms underpinning age-related decreases in muscle strength and muscle mass relate to chronic inflammation. Physical activity induces an anti-inflammatory effect, but it is modulated by additional factors. We hypothesized that vitamin D, which has also anti-inflammatory activity will modify adaptation to exercise and reduce inflammation in elderly women. Twenty-seven women aged 67 ± 8 years were included and divided into groups with baseline vitamin D concentration more than 20 ng mL
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.