ArticleExperimental brain research2017
Organization of the reach and grasp in head-fixed vs freely-moving mice provides support for multiple motor channel theory of neocortical organization.
Article in Experimental brain research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed.
- High-speed neural imaging with multiplexed miniaturized two-photon microscopy.Cell reports methods · 2025Article
- Divergent subregional information processing in mouse prefrontal cortex during working memory.Communications biology · 2024Article
- Divergent Subregional Information Processing in Mouse Prefrontal Cortex During Working Memory.bioRxiv : the preprint server for biology · 2024Article
- Large-scale recording of neuronal activity in freely-moving mice at cellular resolution.Nature communications · 2023Article
- An automated, low-latency environment for studying the neural basis of behavior in freely moving rats.BMC biology · 2023Article
- Task-specific modulation of corticospinal neuron activity during motor learning in mice.Nature communications · 2023Article
- Miniature three-photon microscopy maximized for scattered fluorescence collection.Nature methods · 2023Article
- A deep learning framework for inference of single-trial neural population dynamics from calcium imaging with subframe temporal resolution.Nature neuroscience · 2022Article
- Distributed and Localized Dynamics Emerge in the Mouse Neocortex during Reach-to-Grasp Behavior.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022Article
- Does play shape hand use skill in rats?Experimental brain research · 2021Article
- New roles for dopamine in motor skill acquisition: lessons from primates, rodents, and songbirds.Journal of neurophysiology · 2021Review
- Multichannel near-infrared spectroscopy brain imaging system for small animals in mobile conditions.Neurophotonics · 2021Article
- Dataset of reaching behavior for reward in social situations in mice.Data in brief · 2021Article
- Online control of reach accuracy in mice.Journal of neurophysiology · 2020Article
- Article
- Probing Cortical Activity During Head-Fixed Behavior.Frontiers in molecular neuroscience · 2020Article
- Low-cost solution for rodent home-cage behaviour monitoring.PloS one · 2019Article
- Touch the table before the target: contact with an underlying surface may assist the development of precise visually controlled reach and grasp movements in human infants.Experimental brain research · 2018Article
- Directional Reaching for Water as a Cortex-Dependent Behavioral Framework for Mice.Cell reports · 2018Article
- Frame-by-Frame Video Analysis of Idiosyncratic Reach-to-Grasp Movements in Humans.Journal of visualized experiments : JoVE · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
Multiple motor channel (MMC) theory of neocortical organization proposes that complex movements, such as reaching for a food item to eat, are produced by the coordinated action of separate neural channels. For example, the human reach-to-grasp act is mediated by two visuo-parieto-motor cortex channels, one for the reach and one for the grasp. The present analysis asked whether there is a similar organization of reach-and-grasp movements in the mouse. The reach-to-eat movements of the same mice were examined from high-shutter speed, frame-by-frame video analysis in three tasks in which the mice obtained equivalent success scores: when freely-moving reaching for food pellets, when head-fixed reaching for food pellets, and when head-fixed reaching for pieces of pasta. To reach, the mice used egocentric cues to vary upper arm movements in a task-appropriate manner to place an open hand on the food or to locate the food using a "touch-release-grasp" strategy. Although mice could not hand-shape offline when reaching, they could hand-shape using online touch-related cues from the mouth to manipulate the food at the mouth. That the reach can be performed offline in relation to egocentric cues whereas hand shaping for the grasp requires online cues supports the idea that for the mouse, as for primates, the reach and grasp are separate acts. The results are further discussed in relation to the use of the head-fixed behavioral procedure to identify the independent neural substrates of the reach and the grasp using mesoscale stimulation/imaging methods.
Indexed as
Identifiers
28315945What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.