ArticleNeuroImage2017
Population based MRI and DTI templates of the adult ferret brain and tools for voxelwise analysis.
Article in NeuroImage, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
28 citing papers in PubMed.
- Mechanical deformation explains distinct neuroimaging patterns and etiologies in brain trauma.NeuroImage · 2026Article
- The Impact of Gadolinium on Quantitative Myelin Metrics in Ex Vivo Spinal Cord.NMR in biomedicine · 2026Article
- Investigation of the Relationship Between Skull and Gender of the Sella Turcica in Cats Using Computed Tomography.Veterinary medicine and science · 2026Article
- Ferreting Out the Effects of Neonatal Hypoxia-Ischemia and Sex on Ferret Cortical Gyrification.Life (Basel, Switzerland) · 2025Article
- Evaluation of diffusion time-dependent changes in radial diffusivity as a surrogate for axon diameter.Magnetic resonance in medicine · 2025Article
- Backscattering Mueller matrix polarimetry estimates microscale anisotropy and orientation in complex brain tissue structure.Journal of medical imaging (Bellingham, Wash.) · 2025Article
- An Overview of Anesthetic Procedures for Ferret (Mustela putorius furo) Preclinical Brain MRI: A Call for Standardization.Journal of the American Association for Laboratory Animal Science : JAALAS · 2025Review
- Neuropeptide FF (NPFF)-positive nerve cells of the human cerebral cortex and white matter in controls, selected neurodegenerative diseases, and schizophrenia.Acta neuropathologica communications · 2024Article
- Photoacoustic Tomography with Temporal Encoding Reconstruction (PATTERN) for cross-modal individual analysis of the whole brain.Nature communications · 2024Article
- Evaluating backscattering polarized light imaging microstructural mapping capabilities through neural tissue and analogous phantom imaging.Journal of biomedical optics · 2024Article
- Longitudinal MRI of the developing ferret brain reveals regional variations in timing and rate of growth.Cerebral cortex (New York, N.Y. : 1991) · 2024Article
- Rectal temperature after hypoxia-ischemia predicts white matter and cortical pathology in the near-term ferret.Pediatric research · 2024Article
- Functional ultrasound imaging reveals 3D structure of orientation domains in ferret primary visual cortex.NeuroImage · 2023Article
- Article
- Expression of GFAP and Tau Following Blast Exposure in the Cerebral Cortex of Ferrets.Journal of neuropathology and experimental neurology · 2021Article
- Jacobian Mapping Reveals Converging Brain Substrates of Disruption and Repair in Response to Ethanol Exposure and Abstinence in 2 Strains of Rats.Alcoholism, clinical and experimental research · 2021Article
- The origin and development of subcortical U-fibers in gyrencephalic ferrets.Molecular brain · 2020Article
- Stereotaxic Diffusion Tensor Imaging White Matter Atlas for theFrontiers in neuroanatomy · 2020Article
- The effect of Zika virus infection in the ferret.The Journal of comparative neurology · 2019Article
- Malformations of Human Neocortex in Development - Their Progenitor Cell Basis and Experimental Model Systems.Frontiers in cellular neuroscience · 2019Review
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
Non-invasive imaging has the potential to play a crucial role in the characterization and translation of experimental animal models to investigate human brain development and disorders, especially when employed to study animal models that more accurately represent features of human neuroanatomy. The purpose of this study was to build and make available MRI and DTI templates and analysis tools for the ferret brain as the ferret is a well-suited species for pre-clinical MRI studies with folded cortical surface, relatively high white matter volume and body dimensions that allow imaging with pre-clinical MRI scanners. Four ferret brain templates were built in this study - in-vivo MRI and DTI and ex-vivo MRI and DTI - using brain images across many ferrets and region of interest (ROI) masks corresponding to established ferret neuroanatomy were generated by semi-automatic and manual segmentation. The templates and ROI masks were used to create a web-based ferret brain viewing software for browsing the MRI and DTI volumes with annotations based on the ROI masks. A second objective of this study was to provide a careful description of the imaging methods used for acquisition, processing, registration and template building and to demonstrate several voxelwise analysis methods including Jacobian analysis of morphometry differences between the female and male brain and bias-free identification of DTI abnormalities in an injured ferret brain. The templates, tools and methodological optimization presented in this study are intended to advance non-invasive imaging approaches for human-similar animal species that will enable the use of pre-clinical MRI studies for understanding and treating brain disorders.
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Registered trials
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