Evidence map›Paper›PMID 28315692›Full record

ArticleToxicology and applied pharmacology2017

Role of epithelial-mesenchymal transition (EMT) and fibroblast function in cerium oxide nanoparticles-induced lung fibrosis.

Jane Ma, Bridget Bishoff, R R Mercer, Mark Barger, Diane Schwegler-Berry, Vincent Castranova

Open access · greenAbstract read
In one paragraph

Article in Toxicology and applied pharmacology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 56 citations in OpenAlex.

  1. Adverse effects and underlying mechanism of rare earth elements.Environmental health : a global access science source · 2025
    Pooled it
  2. Modulatory effects of CeOParticle and fibre toxicology · 2026
    Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Cerium Oxide Nanoparticles Alleviate Hepatic Fibrosis Phenotypes In Vitro.International journal of molecular sciences · 2021
    Article
  13. Article
  14. Review
  15. Article
  16. Amphiregulin modulates murine lung recovery and fibroblast function following exposure to agriculture organic dust.American journal of physiology. Lung cellular and molecular physiology · 2020
    Article
  17. Review
  18. Review
  19. Ang-(1-7) treatment attenuates lipopolysaccharide-induced early pulmonary fibrosis.Laboratory investigation; a journal of technical methods and pathology · 2019
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Jane MaHealth Effects Laboratory Division, NIOSH, Morgantown, WV, United States.
Bridget BishoffMylan Pharmaceuticals, Morganntown, WV, United States.
R R MercerHealth Effects Laboratory Division, NIOSH, Morgantown, WV, United States.
Mark BargerHealth Effects Laboratory Division, NIOSH, Morgantown, WV, United States.
Diane Schwegler-BerryHealth Effects Laboratory Division, NIOSH, Morgantown, WV, United States.
Vincent CastranovaSchool of Pharmacy, West Virginia University, Morgantown, WV, United States. Electronic address: vcastran@hsc.wvu.edu.
National Institute for Occupational Safety and Health · USMylan (United States) · USWest Virginia University · US

Funding

Intramural CDC HHS CC999999
6 · The paper itself

Abstract

The emission of cerium oxide nanoparticles (CeO

Indexed as

ActinsAlveolar Epithelial CellsAnimalsBronchoalveolar Lavage FluidCells, CulturedCell ShapeCeriumCollagenEpithelial-Mesenchymal TransitionFibroblastsHydroxyprolineLungMaleMetal NanoparticlesPeptidesPulmonary FibrosisActa2 protein, ratActinsceric oxideCeriumCollagenHydroxyprolinePeptidesSftpc protein, ratTransforming Growth Factor betaCerium oxideEpithelial cellsEpithelial-mesenchymal transitionLung fibrosisNanoparticles

Identifiers

PMID28315692
PMCPMC6341478
OpenAlexW2596596967

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.