ArticlePlanta2017
Genetic diversity and metabolic profile of Salvia officinalis populations: implications for advanced breeding strategies.
Article in Planta, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Article
- Evaluation ofPlants (Basel, Switzerland) · 2026Article
- Decoding the mitogenome of rosemary (Salvia rosmarinus): insights into genome evolution, structural dynamics and prospects for mitochondrial engineering.BMC plant biology · 2025Article
- Screening of native wild Salvia nemorosa populations for chemical compositions, antioxidant activity and UHPLC-HRMS profiling.Scientific reports · 2024Article
- Enhancement of Essential Oil Production and Expression of Some Menthol Biosynthesis-Related Genes inIranian journal of biotechnology · 2023Article
- Mitochondrial Genome Sequence ofInternational journal of molecular sciences · 2023Article
- Genetic and Metabolite Variability among Commercial Varieties and Advanced Lines ofPlants (Basel, Switzerland) · 2023Article
- A Validated Method for the Determination of Carnosic Acid and Carnosol in the Fresh Foliage of Salvia rosmarinus and Salvia officinalis from GreecePlants (Basel, Switzerland) · 2022Article
- The chromosome-level genome foriScience · 2022Article
- Metabolomics Study of Different Germplasm Resources for ThreeFrontiers in plant science · 2022Article
- Article
- Cloning and Characterization of 1,8-Cineole Synthase (Frontiers in plant science · 2022Article
- Lignans of Sesame (Molecules (Basel, Switzerland) · 2021Review
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
MAIN
conclusionAs a result of this work, we were able to characterize seven indigenous to Greece Salvia officinalis populations using genetic and metabolomic tools. These tools can be used to select the most promising genotypes, capable to design future breeding programs for high valuable varieties. An initial investigation was carried out to compare the genetic and metabolic diversity in S. officinalis grown in Greece and to discern the relationship between the two sets of data. Analysis of inter-simple sequence repeats (ISSR) revealed significant genetic differences among seven sage populations, which were grouped into three main clusters according to an UPGMA ISSR data-based dendrogram and Principle Coordinate Analysis. 80 loci were scored of which up to 90% were polymorphic at species level. According to the composition of their essential oil, the populations were classified into two chemotypes: 1.8 cineole/α-thujone and α-thujone/1.8 cineole. Additionally, a targeted ultra performance liquid chromatography (UPLC-MS/MS) method was used to qualify and quantify phenolic compounds in methanolic extracts of the seven sage genotypes according to which they were districted in six clusters among the sage populations. The main compounds characterizing the seven genotypes were rosmarinic acid and carnosol, followed by apigenin-7-O-glucoside (Ap7glc), and luteolin-7-O-glucoside (Lu7glc). The correlation between matrices obtained from ISSR data and metabolic profiles was non-significant. However, based on the differences in metabolic fingerprint, we aimed to define populations using as main selection criteria the high polyphenol content and desired essential oil composition, using state to the art analytical tools for the identification of parent lines for breeding programs.
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