Evidence map›Paper›PMID 28314854›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2017

Common nonmutational

Giulia Fabbri, Antony B Holmes, Mara Viganotti, Claudio Scuoppo, Laura Belver, Daniel Herranz, Xiao-Jie Yan, Yasmine Kieso, Davide Rossi, Gianluca Gaidano and 3 more

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 80 papers.

0numbers the graph read from it
0cells of the map it votes in
80citing papers in PubMed
8.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

80 citing papers in PubMed, 126 citations in OpenAlex.

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  17. PeerJ · 2024
    Article
  18. Article
  19. Frontiers in oncology · 2023
    Article
  20. Article

20 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 3 countries.

Giulia FabbriInstitute for Cancer Genetics and the Herbert Irving Comprehensive Cancer Center, Columbia University, New York, NY 10032.
Antony B HolmesInstitute for Cancer Genetics and the Herbert Irving Comprehensive Cancer Center, Columbia University, New York, NY 10032.
Mara ViganottiInstitute for Cancer Genetics and the Herbert Irving Comprehensive Cancer Center, Columbia University, New York, NY 10032.
Claudio ScuoppoInstitute for Cancer Genetics and the Herbert Irving Comprehensive Cancer Center, Columbia University, New York, NY 10032.
Laura BelverInstitute for Cancer Genetics and the Herbert Irving Comprehensive Cancer Center, Columbia University, New York, NY 10032.
Daniel HerranzInstitute for Cancer Genetics and the Herbert Irving Comprehensive Cancer Center, Columbia University, New York, NY 10032.
Xiao-Jie YanThe Feinstein Institute for Medical Research, Northwell Health, Manhasset, New York, NY 11030.
Yasmine KiesoThe Feinstein Institute for Medical Research, Northwell Health, Manhasset, New York, NY 11030.
Davide RossiDivision of Hematology, Oncology Institute of Southern Switzerland, 6500 Bellinzona, Switzerland.
Gianluca GaidanoDivision of Haematology, Department of Translational Medicine, Università del Piemonte Orientale, 28100 Novara, Italy.
Nicholas ChiorazziThe Feinstein Institute for Medical Research, Northwell Health, Manhasset, New York, NY 11030.
Adolfo A FerrandoInstitute for Cancer Genetics and the Herbert Irving Comprehensive Cancer Center, Columbia University, New York, NY 10032.
Riccardo Dalla-FaveraInstitute for Cancer Genetics and the Herbert Irving Comprehensive Cancer Center, Columbia University, New York, NY 10032; rd10@columbia.edu.
Columbia University · USNorthwell Health · USCancer Genetics (United States) · USInstitute of Oncology Research · CHUniversità degli Studi del Piemonte Orientale “Amedeo Avogadro” · IT

Funding

Molecular pathways and targeted therapies in human leukemiaR35CA210065 · NCI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI FERRANDO, ADOLFO A. · 2017 to 2021
$4.7M
The Role of NOTCH1 in the Pathogenesis of CLL.R01CA177319 · NCI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI DALLA-FAVERA, RICCARDO, FERRANDO, ADOLFO A. · 2013 to 2017
$1.8M
Functional dissection of oncogenic enhancersR00CA197869 · NCI · RBHS -CANCER INSTITUTE OF NEW JERSEY · PI HERRANZ, DANIEL · 2017 to 2019
$747k
Functional dissection of oncogenic enhancersK99CA197869 · NCI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI HERRANZ, DANIEL · 2015 to 2016
$342k
NCI NIH HHS K99 CA197869NCI NIH HHS R00 CA197869NCI NIH HHS R01 CA177319NCI NIH HHS R35 CA210065
6 · The paper itself

Abstract

Activating mutations of

Indexed as

B-LymphocytesCell ProliferationGene Expression Regulation, LeukemicGenes, mycHumansLeukemia, Lymphocytic, Chronic, B-CellMutationReceptor, Notch1NOTCH1 protein, humanReceptor, Notch1chronic lymphocytic leukemiaNOTCH1transcriptional network

Identifiers

PMID28314854
PMCPMC5389283
OpenAlexW2597022636

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.