Evidence map›Paper›PMID 28314735›Full record

ReviewGut2017

Non-alcoholic fatty liver disease and its relationship with cardiovascular disease and other extrahepatic diseases.

Leon A Adams, Quentin M Anstee, Herbert Tilg, Giovanni Targher

Registry-linked trialOpen access · bronzeAbstract readReview
PubMed Publisher
In one paragraph

Review in Gut, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06739486 (Efficacy of Sodium Glucose Cotransporter 2 Inhibitors on Non-Alcoholic Fatty Liver Disease), which is not on this map. Cited by 566 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
566citing papers in PubMed, 7 pooled it
64.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06739486 not yet recruitingnot on this mapstarted 2024, after this paper: background citation

Efficacy of Sodium Glucose Cotransporter 2 Inhibitors on Non-Alcoholic Fatty Liver Disease

TypeobservationalSponsorAssiut UniversityRan2024 to 2025Enrolled100ConditionsNon Alcholic Fatty Liver Disease, Hepatic Steatosis, Hepatic Fibrosis, NAFLD (Nonalcoholic Fatty Liver Disease)
3 · Its place in the literature

Who cites it

566 citing papers in PubMed, 7 syntheses or guidelines pooled it, 1,173 citations in OpenAlex.

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  11. Steatotic liver disease in Latin America: current views and perspectives.Nature reviews. Gastroenterology & hepatology · 2026
    Review
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506 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 4 countries.

Leon A AdamsSchool of Medicine and Pharmacology, The University of Western Australia, Nedlands, Western Australia, Australia.
Quentin M AnsteeFaculty of Medical Sciences, Institute of Cellular Medicine, Newcastle University, Newcastle Upon Tyne, UK.
Herbert TilgDepartment of Internal Medicine I, Gastroenterology, Hepatology & Metabolism, Medical University Innsbruck, Innsbruck, Austria.
Giovanni TargherDivision of Endocrinology, Diabetes and Metabolism, Department of Medicine, University and Azienda Ospedaliera Universitaria Integrata of Verona, Verona, Italy.
Azienda Ospedaliera Universitaria Integrata Verona · ITInnsbruck Medical University · ATNewcastle University · GBUniversity of Western Australia · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Key physiological functions of the liver, including glucose and lipid metabolism, become disturbed in the setting of non-alcoholic fatty liver disease (NAFLD) and may be associated with a systemic inflammatory '

Indexed as

AdipokinesAnimalsCardiovascular DiseasesColorectal NeoplasmsCytokinesDiabetes Mellitus, Type 2DietGastrointestinal MicrobiomeHumansIncidenceNon-alcoholic Fatty Liver DiseaseNutritional StatusOsteoporosisPrevalenceRenal Insufficiency, ChronicRisk FactorsAdipokinesCytokinesCARDIOVASCULAR DISEASEDIABETES MELLITUSNONALCOHOLIC STEATOHEPATITIS

Identifiers

PMID28314735
OpenAlexW2595016203

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.