Evidence map›Paper›PMID 28314574›Full record

ArticleKidney international2017

APOL1: a case in point for replacing race with genetics.

Girish N Nadkarni, Christina M Wyatt, Barbara Murphy, Michael J Ross

Abstract readComment
PubMed Publisher
In one paragraph

Article in Kidney international, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Kidney international reports · 2020
    Article
  3. APOL1-Associated Nephropathy: A Key Contributor to Racial Disparities in CKD.American journal of kidney diseases : the official journal of the National Kidney Foundation · 2018
    Review
  4. Hypertension in African Americans.Current cardiology reports · 2017
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Girish N NadkarniDivision of Nephrology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA. Electronic address: girish.nadkarni@mssm.edu.
Christina M WyattDivision of Nephrology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Barbara MurphyDivision of Nephrology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Michael J RossDivision of Nephrology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Icahn School of Medicine at Mount Sinai · US

Funding

Novel mechanisms of antiretroviral protection against HIV-related kidney diseasesR01DK101338 · NIDDK · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI ROSS, MICHAEL J · 2014 to 2018
$1.9M
The role of APOL1 polymorphisms in promoting HIV-related kidney injuryR01DK108346 · NIDDK · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI ROSS, MICHAEL J · 2015 to 2019
$1.6M
Risk Clustering and Stratification in Genetically High-Risk Individuals Using Electronic Medical Records and BiomarkersK23DK107908 · NIDDK · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI NADKARNI, GIRISH NITIN · 2016 to 2020
$930k
NIDDK NIH HHS K23 DK107908NIDDK NIH HHS R01 DK101338NIDDK NIH HHS R01 DK108346
6 · The paper itself

Abstract

Ethnicity-specific differences in apolipoprotein L1 (APOL1) polymorphisms are associated with racial disparities in kidney transplantation outcomes. APOL1 genotyping may better help define graft outcome risk pre-transplantation; however, more research is needed.

Indexed as

Genetic TestingKidney TransplantationPolymorphism, GeneticRacial GroupsTissue DonorsApolipoprotein L1ApolipoproteinsDonor SelectionGenotypeGraft SurvivalHumansLipoproteins, HDLPhenotypePostoperative ComplicationsRisk AssessmentRisk FactorsAPOL1 protein, humanApolipoprotein L1ApolipoproteinsLipoproteins, HDL

Identifiers

PMID28314574
OpenAlexW2601100983

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.