Evidence map›Paper›PMID 28314470›Full record

ReviewMedecine et maladies infectieuses2017

Infectious encephalitis: Management without etiological diagnosis 48hours after onset.

P Fillatre, Y Crabol, P Morand, L Piroth, J Honnorat, J P Stahl, M Lecuit

Abstract readReview
In one paragraph

Review in Medecine et maladies infectieuses, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Tick-Borne Encephalitis (TBE): From Tick to Pathology.Journal of clinical medicine · 2023
    Review
  3. Review
  4. Review
  5. Article
  6. Review
  7. Review
  8. Epidemiological Profile of Acute Viral Encephalitis in a Sample of Egyptian Children.Open access Macedonian journal of medical sciences · 2018
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

P FillatreService de maladies infectieuses et réanimation médicale, CHU Pontchaillou, 35000 Rennes, France.
Y CrabolMédecine interne, CHBUA site de Vannes, 56017 Vannes, France.
P MorandVirologie, CHU Grenoble Alpes, 38043 Grenoble cedex 9, France.
L PirothInfectiologie, CHU de Dijon, 21000 Dijon, France.
J HonnoratInserm U1028, CNRS UMR5292, équipe neuro-oncologie et neuro-inflammation (Oncoflam), centre de recherche en neurosciences (CRNL), université Lyon 1, 69500 Bron, France.
J P StahlService d'infectiologie, CHU de Grenoble, 38043 Grenoble cedex 9, France. Electronic address: jpstahl@chu-grenoble.fr.
M LecuitInstitut Pasteur, Biology of Infection Unit, CNR CCOMS Listeria, Inserm U1117, Paris, France; Paris Descartes University, Sorbonne Paris Cité, Department of Infectious Diseases and Tropical Medicine, Necker-Enfants-Malades University Hospital, Institut Imagine, Assistance Publique-Hôpitaux de Paris, Paris, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe etiological diagnosis of infectious encephalitis is often not established 48hours after onset. We aimed to review existing literature data before providing management guidelines.

methodWe performed a literature search on PubMed using filters such as "since 01/01/2000", "human", "adults", "English or French", and "clinical trial/review/guidelines". We also used the Mesh search terms "encephalitis/therapy" and "encephalitis/diagnosis".

resultsWith Mesh search terms "encephalitis/therapy" and "encephalitis/diagnosis", we retrieved 223 and 258 articles, respectively. With search terms "encephalitis and corticosteroid", we identified 38 articles, and with "encephalitis and doxycycline" without the above-mentioned filters we identified 85 articles. A total of 210 articles were included in the analysis. DISCUSSION: Etiological investigations must focus on recent travels, animal exposures, age, immunodeficiency, neurological damage characteristics, and potential extra-neurological signs. The interest of a diagnosis of encephalitis for which there is no specific treatment is also to discontinue any empirical treatments initially prescribed. Physicians must consider and search for autoimmune encephalitis.

Indexed as

AdultAnti-Infective AgentsAutoimmune Diseases of the Nervous SystemDiagnosis, DifferentialDisease ManagementHumansInfectious EncephalitisTime FactorsAnti-Infective AgentsEncéphalite infectieuseHSVInfectious encephalitisListeriaTuberculoseTuberculosisVZV

Identifiers

PMID28314470
PMCPMC7131623

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.