Evidence map›Paper›PMID 28314368›Full record

ArticleNanoscale research letters2017

Metallic nanoparticles reduce the migration of human fibroblasts in vitro.

Larissa Fernanda de Araújo Vieira, Marvin Paulo Lins, Iana Mayane Mendes Nicácio Viana, Jeniffer Estevão Dos Santos, Salete Smaniotto, Maria Danielma Dos Santos Reis

Open access · goldAbstract read
In one paragraph

Article in Nanoscale research letters, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 54 citations in OpenAlex.

  1. Review
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  8. Review
  9. Cancer Therapy by Silver Nanoparticles: Fiction or Reality?International journal of molecular sciences · 2022
    Review
  10. Cytotoxicity of Hybrid Noble Metal-Polymer Composites.BioMed research international · 2022
    Article
  11. Silver Nanoparticles Formation byNanomaterials (Basel, Switzerland) · 2021
    Article
  12. Review
  13. Article
  14. Biological Potential of Silver Nanoparticles Mediated byNanomaterials (Basel, Switzerland) · 2021
    Article
  15. Article
  16. Review
  17. Article
  18. Dual-action of thermoresponsive gels containing DsiRNA-loaded gold nanoparticles for diabetic wound therapy: Characterization,Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2020
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Larissa Fernanda de Araújo VieiraLaboratory of Cell Biology, Institute of Biological Sciences and Health, Federal University of Alagoas, CEP 57072-970, Maceió, Alagoas, Brazil.
Marvin Paulo LinsLaboratory of Cell Biology, Institute of Biological Sciences and Health, Federal University of Alagoas, CEP 57072-970, Maceió, Alagoas, Brazil.
Iana Mayane Mendes Nicácio VianaLaboratory of Cell Biology, Institute of Biological Sciences and Health, Federal University of Alagoas, CEP 57072-970, Maceió, Alagoas, Brazil.
Jeniffer Estevão Dos SantosLaboratory of Cell Biology, Institute of Biological Sciences and Health, Federal University of Alagoas, CEP 57072-970, Maceió, Alagoas, Brazil.
Salete SmaniottoLaboratory of Cell Biology, Institute of Biological Sciences and Health, Federal University of Alagoas, CEP 57072-970, Maceió, Alagoas, Brazil.
Maria Danielma Dos Santos ReisLaboratory of Cell Biology, Institute of Biological Sciences and Health, Federal University of Alagoas, CEP 57072-970, Maceió, Alagoas, Brazil. danielma.reis@icbs.ufal.br.
Universidade Federal de Alagoas · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nanoparticles have extremely wide applications in the medical and biological fields. They are being used in biosensors, local drug delivery, diagnostics, and medical therapy. However, the potential effects of nanoparticles on target cell and tissue function, apart from cytotoxicity, are not completely understood. Thus, the aim of this study was to investigate the in vitro effects of silver nanoparticles (AgNPs) and gold nanoparticles (AuNPs) on human fibroblasts with respect to their interaction with the extracellular matrix and in cell migration. Immunofluorescence analysis revealed that treatment with AgNPs or AuNPs decreased collagen and laminin production at all the concentrations tested (0.1, 1, and 10 μg/mL). Furthermore, cytofluorometric analysis showed that treatment with AgNPs reduced the percentage of cells expressing the collagen receptor very late antigen 2, α

Indexed as

Cell migrationCytoskeletonExtracellular matrixFibroblastGold nanoparticlesSilver nanoparticles

Identifiers

PMID28314368
PMCPMC5355407
OpenAlexW2595062697

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.