Evidence map›Paper›PMID 28314081›Full record

ArticleClinical transplantation2017

Delirium after lung transplantation: Association with recipient characteristics, hospital resource utilization, and mortality.

Yelizaveta Sher, Joshua Mooney, Gundeep Dhillon, Roy Lee, José R Maldonado

Open access · greenAbstract read
In one paragraph

Article in Clinical transplantation, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Medical Complications of Lung Transplantation.Journal of chest surgery · 2022
    Article
  7. Non-pulmonary complications after lung transplantation: Part I.Indian journal of thoracic and cardiovascular surgery · 2022
    Review
  8. Consensus document for the selection of lung transplant candidates: An update from the International Society for Heart and Lung Transplantation.The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · 2021
    Article
  9. Article
  10. Article
  11. Clinical and Neuroimaging Correlates of Post-Transplant Delirium.Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation · 2020
    Article
  12. Article
  13. Article
  14. Incidence, Risk Factors, and Sequelae of Post-kidney Transplant Delirium.Journal of the American Society of Nephrology : JASN · 2018
    Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Yelizaveta SherDepartment of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA, USA.ORCID 0000-0001-8127-5580
Joshua MooneyDepartment of Medicine, Stanford University, Stanford, CA, USA.
Gundeep DhillonDepartment of Medicine, Stanford University, Stanford, CA, USA.
Roy LeeDepartment of Pharmacy, Stanford Health Care, Stanford, CA, USA.
José R MaldonadoDepartment of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA, USA.
Stanford University · USStanford Health Care · US

Funding

Spectrum Stanford Center for clinical and Translational Research and EducationKL2TR001083 · NCATS · STANFORD UNIVERSITY · PI CULLEN, MARK RICHARD, GREENBERG, HARRY BERNARD · 2013 to 2017
$4.9M
NCATS NIH HHS KL2 TR001083
6 · The paper itself

Abstract

backgroundDelirium is associated with increased morbidity and mortality. The factors associated with post-lung transplant delirium and its impact on outcomes are under characterized.

methodsThe medical records of 163 consecutive adult lung transplant recipients were reviewed for delirium within 5 days (early-onset) and 30 hospital days (ever-onset) post-transplantation. A multivariable logistic regression model assessed factors associated with delirium. Multivariable negative binomial regression and Cox proportional hazards models assessed the association of delirium with ventilator duration, intensive care unit (ICU) length of stay (LOS), hospital LOS, and one-year mortality.

resultsThirty-six percent of patients developed early-onset, and 44% developed ever-onset delirium. Obesity (OR 6.35, 95% CI 1.61-24.98) and bolused benzodiazepines within the first postoperative day (OR 2.28, 95% CI 1.07-4.89) were associated with early-onset delirium. Early-onset delirium was associated with longer adjusted mechanical ventilation duration (P=.001), ICU LOS (P<.001), and hospital LOS (P=.005). Ever-onset delirium was associated with longer ICU (P<.001) and hospital LOS (P<.001). After adjusting for clinical variables, delirium was not significantly associated with one-year mortality (early-onset HR 1.65, 95% CI 0.67-4.03; ever-onset HR 1.70, 95% CI 0.63-4.55).

conclusionsDelirium is common after lung transplant surgery and associated with increased hospital resources.

Indexed as

Postoperative ComplicationsTransplant RecipientsDeliriumFemaleFollow-Up StudiesHealth ResourcesHospital MortalityHumansIntensive Care UnitsLength of StayLung TransplantationMaleMiddle AgedPrognosisRespiration, ArtificialRetrospective Studiescognitive disorderdeliriumdelirium outcomeslung transplantlung transplantation

Identifiers

PMID28314081
PMCPMC5509889
OpenAlexW2596021388

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.