Evidence map›Paper›PMID 28305631›Full record

ArticleRoux's archives of developmental biology : the official organ of the EDBO1988

Electrically mediated protein movement inDrosophila follicles.

Richard I Woodruff, James H Kulp, Eric D LaGaccia

Abstract read
PubMed Publisher
In one paragraph

Article in Roux's archives of developmental biology : the official organ of the EDBO, 1988. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. Particle tracking model of electrophoretic morphogen movement reveals stochastic dynamics of embryonic gradient.Developmental dynamics : an official publication of the American Association of Anatomists · 2009
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Richard I WoodruffDepartment of Biology, West Chester University, 19383, West Chester, PA, USA.
James H KulpDepartment of Biology, West Chester University, 19383, West Chester, PA, USA.
Eric D LaGacciaDepartment of Biology, West Chester University, 19383, West Chester, PA, USA.
West Chester University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Distribution of rhodamine-conjugated lysozyme injected into the sixteen-cell syncytium comprising the germ-line portion of theDrosophila follicle is shown to be affected by charge. Positive molecules are able to migrate through intercellular bridges from the oocyte to the nurse cells, but are unable to migrate detectably from nurse cells to the oocyte. Their negatively charged counterparts can move from the nurse cells to the oocyte, but are unable to traverse the intercellular bridges in the counter direction. This charge-dependent movement of molecules is accompanied by an electrical potential difference, focused across the nurse cell-oocyte bridges, which makes the nurse cells negatively charged to the oocyte. The addition of insect hemolymph to the physiological salt solution in which the experiments were performed resulted in only a small increase in the transmembrane resistance, but enhanced the potential difference between oocyte and nurse cells from 0.2±0.3 (SE) mV (nurse cells negative) to 2.3±0.45 (SE) mV (nurse cells negative).

Indexed as

DrosophilaElectrical polarityOvarian follicles

Identifiers

PMID28305631
OpenAlexW1990467117

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.