Evidence map›Paper›PMID 28304404›Full record

ArticleCell death and differentiation2017

Interactions between Th1 cells and Tregs affect regulation of hepatic fibrosis in biliary atresia through the IFN-γ/STAT1 pathway.

Jie Wen, Ying Zhou, Jun Wang, Jie Chen, Wenbo Yan, Jin Wu, Junkai Yan, Kejun Zhou, Yongtao Xiao, Yang Wang and 2 more

RetractedOpen access · hybridAbstract readRetracted Publication
In one paragraph

Article in Cell death and differentiation, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
4.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.

  1. Pooled it
  2. The Immune Microenvironment: New Therapeutic Implications in Organ Fibrosis.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Review
  3. Identifying TNFSF4Stem cell research & therapy · 2025
    Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Environment, Epigenetics, and Differential Responses to Beryllium Exposure: Are We There Yet?American journal of respiratory cell and molecular biology · 2019
    Article
  15. CD4Frontiers in pediatrics · 2019
    Article
  16. Article
  17. Review
  18. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Jie WenDepartment of Pediatric Surgery, Xin Hua Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Ying ZhouDepartment of Pediatric Surgery, Xin Hua Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Jun WangDepartment of Pediatric Surgery, Xin Hua Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Jie ChenDepartment of Pediatric Surgery, Xin Hua Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Wenbo YanDepartment of Pediatric Surgery, Xin Hua Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Jin WuShanghai Key Laboratory of Pediatric Gastroenterology and Nutrition, Shanghai, China.
Junkai YanShanghai Key Laboratory of Pediatric Gastroenterology and Nutrition, Shanghai, China.
Kejun ZhouShanghai Key Laboratory of Pediatric Gastroenterology and Nutrition, Shanghai, China.
Yongtao XiaoShanghai Key Laboratory of Pediatric Gastroenterology and Nutrition, Shanghai, China.
Yang WangShanghai Key Laboratory of Pediatric Gastroenterology and Nutrition, Shanghai, China.
Qiang XiaDepartment of Liver Surgery, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Wei CaiDepartment of Pediatric Surgery, Xin Hua Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Shanghai Institute of Nutrition and Health · CNShanghai Jiao Tong University · CNXinHua Hospital · CNRenji Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Regulatory T cells (Tregs) and CD4

Indexed as

Signal TransductionBiliary AtresiaCell ProliferationHepatic Stellate CellsHumansInfantInterferon-gammaLiver CirrhosisSTAT1 Transcription FactorTh1 CellsT-Lymphocytes, RegulatoryInterferon-gammaSTAT1 protein, humanSTAT1 Transcription Factor

Identifiers

PMID28304404
PMCPMC5442468
OpenAlexW2597001181

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.