ArticleScientific reports2017
Chemical profiling analysis of Maca using UHPLC-ESI-Orbitrap MS coupled with UHPLC-ESI-QqQ MS and the neuroprotective study on its active ingredients.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.
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Who cites it
31 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pooled it
- Antitumor-Relevant Evaluation of Liquid and MicroencapsulatedMolecules (Basel, Switzerland) · 2026Article
- Maca (Foods (Basel, Switzerland) · 2026Review
- Purification of Lepidilines A, B, C, and D fromMolecules (Basel, Switzerland) · 2025Article
- Antioxidant, Neuroprotective, and Antinociceptive Effects of Peruvian Black Maca (Antioxidants (Basel, Switzerland) · 2025Article
- Chemical profiling, antioxidant, and antibacterial properties ofFrontiers in nutrition · 2025Article
- Synergism of Specific Maca Phenotypes (Molecules (Basel, Switzerland) · 2024Article
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- Potential Surviving Effect ofAntibiotics (Basel, Switzerland) · 2024Article
- Non-invasive prediction of maca powder adulteration using a pocket-sized spectrophotometer and machine learning techniques.Scientific reports · 2024Article
- Not All Maca Is Created Equal: A Review of Colors, Nutrition, Phytochemicals, and Clinical Uses.Nutrients · 2024Review
- Exploring the chemical and pharmacological variability ofFrontiers in pharmacology · 2024Review
- The Efficient Synthesis and Anti-Fatigue Activity Evaluation of Macamides: The Unique Bioactive Compounds in Maca.Molecules (Basel, Switzerland) · 2023Article
- Nootropic Herbs, Shrubs, and Trees as Potential Cognitive Enhancers.Plants (Basel, Switzerland) · 2023Review
- Article
- The Distribution of Glucosinolates in Different Phenotypes ofInternational journal of molecular sciences · 2022Article
- Comprehensive Profiling of Macamides and Fatty Acid Derivatives in Maca with Different Postharvest Drying Processes Using UPLC-QTOF-MS.ACS omega · 2021Article
- MacathiohydantoinMolecules (Basel, Switzerland) · 2021Article
- Maca extracts regulate glucose and lipid metabolism in insulin-resistant HepG2 cells via the PI3K/AKT signalling pathway.Food science & nutrition · 2021Article
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Lepidium meyenii (Maca), originated from Peru, has been cultivated widely in China as a popular health care food. However, the chemical and effective studies of Maca were less in-depth, which restricted its application seriously. To ensure the quality of Maca, a feasible and accurate strategy was established. One hundred and sixty compounds including 30 reference standards were identified in 6 fractions of methanol extract of Maca by UHPLC-ESI-Orbitrap MS. Among them, 15 representative active compounds were simultaneously determined in 17 samples by UHPLC-ESI-QqQ MS. The results suggested that Maca from Yunnan province was the potential substitute for the one from Peru. Meanwhile, the neuroprotective effects of Maca were investigated. Three fractions and two pure compounds showed strong activities in the 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine (MPTP)-induced zebrafish model. Among them, 80% methanol elution fraction (Fr
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