Evidence map›Paper›PMID 28304369›Full record

ArticleThe ISME journal2017

The role of adaptive immunity as an ecological filter on the gut microbiota in zebrafish.

Keaton Stagaman, Adam R Burns, Karen Guillemin, Brendan Jm Bohannan

Open access · bronzeAbstract read
In one paragraph

Article in The ISME journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
67citing papers in PubMed, 1 pooled it
5.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

67 citing papers in PubMed, 1 synthesis or guideline pooled it, 123 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. The island biology of the host microbiome.Trends in microbiology · 2026
    Review
  6. Review
  7. Article
  8. Article
  9. DRIVERS OF VARIATION OF THE ZEBRAFISH EGG MICROBIOME.bioRxiv : the preprint server for biology · 2025
    Article
  10. Article
  11. Review
  12. Review
  13. Review
  14. Article
  15. Review
  16. Article
  17. Review
  18. Review
  19. Article
  20. Review

7 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Keaton StagamanInstitute of Ecology and Evolution, University of Oregon, Eugene, OR, USA.
Adam R BurnsInstitute of Ecology and Evolution, University of Oregon, Eugene, OR, USA.
Karen GuilleminInstitute of Molecular Biology, University of Oregon, Eugene, OR, USA.
Brendan Jm BohannanInstitute of Ecology and Evolution, University of Oregon, Eugene, OR, USA.
University of Oregon · US

Funding

Zebrafish FacilityP01HD022486 · NICHD · UNIVERSITY OF OREGON · PI EISEN, JUDITH S · 1987 to 2017
$28.8M
Research Area IIIP50GM098911 · NIGMS · UNIVERSITY OF OREGON · PI PARTHASARATHY, RAGHUVEER · 2012 to 2016
$9.8M
Graduate Training in Genetics Administrative Supplement - Career Curriculum DevelopmentT32GM007413 · NIGMS · UNIVERSITY OF OREGON · PI GUILLEMIN, KAREN J · 1985 to 2022
$7.8M
Microbial Ecology of the Zebrafish IntestineR01GM095385 · NIGMS · UNIVERSITY OF OREGON · PI BOHANNAN, BRENDAN, GUILLEMIN, KAREN J · 2011 to 2014
$1.4M
NICHD NIH HHS P01 HD022486NIGMS NIH HHS P50 GM098911NIGMS NIH HHS R01 GM095385NIGMS NIH HHS T32 GM007413
6 · The paper itself

Abstract

All animals live in intimate association with communities of microbes, collectively referred to as their microbiota. Certain host traits can influence which microbial taxa comprise the microbiota. One potentially important trait in vertebrate animals is the adaptive immune system, which has been hypothesized to act as an ecological filter, promoting the presence of some microbial taxa over others. Here we surveyed the intestinal microbiota of 68 wild-type zebrafish, with functional adaptive immunity, and 61 rag1

Indexed as

Adaptive ImmunityAnimalsGastrointestinal MicrobiomeGene DeletionGenotypeHomeodomain ProteinsMicrobiotaPhylogenyZebrafishHomeodomain ProteinsRAG-1 protein

Identifiers

PMID28304369
PMCPMC5520148
OpenAlexW2596137760

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.