Evidence map›Paper›PMID 28304335›Full record

ReviewNutrients2017

The Relationship between Fatty Acids and Different Depression-Related Brain Regions, and Their Potential Role as Biomarkers of Response to Antidepressants.

Maria Fernanda Fernandes, David M Mutch, Francesco Leri

Open access · goldAbstract readReview
In one paragraph

Review in Nutrients, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed, 1 pooled it
5.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 1 synthesis or guideline pooled it, 86 citations in OpenAlex.

  1. Pooled it
  2. Trial
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  5. Article
  6. Article
  7. Article
  8. Genetic and Functional Dissection of the NFKB2 Gene: Implications for Milk Fatty Acid Biosynthesis in Dairy Cattle.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025
    Article
  9. Article
  10. Article
  11. Gut microbiota, nutrients, and depression.Frontiers in nutrition · 2025
    Review
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Maria Fernanda FernandesDepartment of Psychology and Neuroscience, University of Guelph, Guelph, ON N1G 2W1, Canada. mariafer@uoguelph.ca.
David M MutchDepartment of Human Health and Nutritional Sciences, University of Guelph, Guelph, ON N1G 2W1, Canada. dmutch@uoguelph.ca.
Francesco LeriDepartment of Psychology and Neuroscience, University of Guelph, Guelph, ON N1G 2W1, Canada. fleri@uoguelph.ca.
University of Guelph · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Depression is a complex disorder influenced by a variety of biological and environmental factors. Due to significant heterogeneity, there are remarkable differences in how patients respond to treatment. A primary objective of psychiatric research is to identify biological markers that could be used to better predict and enhance responses to antidepressant treatments. Diet impacts various aspects of health, including depression. The fatty acid composition of the Western diet, which has a high ratio of

Indexed as

AnimalsAntidepressive AgentsBiomarkersBrainDepressionDietary FatsDisease Models, AnimalFatty AcidsFatty Acids, Omega-3Fatty Acids, Omega-6HumansAntidepressive AgentsBiomarkersDietary FatsFatty AcidsFatty Acids, Omega-3Fatty Acids, Omega-6antidepressantsdietfatty acidshippocampusHPA-axismental healthmental illnessprefrontal cortexstriatum

Identifiers

PMID28304335
PMCPMC5372961
OpenAlexW2596616464

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.