Evidence map›Paper›PMID 28304032›Full record

ArticleChemical communications (Cambridge, England)2017

Facile synthesis of chlorin bioconjugates by a series of click reactions.

Junior Gonzales, N V S Dinesh K Bhupathiraju, William Perea, Huong Chu, Naxhije Berisha, Veronica Bueno, Naser Dodic, Julia Rozenberg, Nancy L Greenbaum, Charles Michael Drain

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Chemical communications (Cambridge, England), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. NabioRxiv : the preprint server for biology · 2024
    Article
  3. Synthesis of new representatives of ABeilstein journal of organic chemistry · 2024
    Article
  4. Development and Validation of Nerve-Targeted Bacteriochlorin Sensors.Journal of the American Chemical Society · 2023
    Article
  5. Article
  6. Review
  7. Article
  8. Leveraging synthetic chlorins for bio-imaging applications.Chemical communications (Cambridge, England) · 2020
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Junior GonzalesDepartment of Chemistry, Hunter College of the City University of New York, 695 Park Avenue, New York, New York 10065, USA. cdrain@hunter.cuny.edu and Chemistry Program, Graduate Center of the City University of New York, 365 5th Avenue, New York, New York 10016, USA.
N V S Dinesh K BhupathirajuDepartment of Chemistry, Hunter College of the City University of New York, 695 Park Avenue, New York, New York 10065, USA. cdrain@hunter.cuny.edu.
William PereaDepartment of Chemistry, Hunter College of the City University of New York, 695 Park Avenue, New York, New York 10065, USA. cdrain@hunter.cuny.edu.
Huong ChuDepartment of Chemistry, Hunter College of the City University of New York, 695 Park Avenue, New York, New York 10065, USA. cdrain@hunter.cuny.edu and Chemistry Program, Graduate Center of the City University of New York, 365 5th Avenue, New York, New York 10016, USA.
Naxhije BerishaDepartment of Chemistry, Hunter College of the City University of New York, 695 Park Avenue, New York, New York 10065, USA. cdrain@hunter.cuny.edu.
Veronica BuenoDepartment of Chemistry, Hunter College of the City University of New York, 695 Park Avenue, New York, New York 10065, USA. cdrain@hunter.cuny.edu.
Naser DodicDepartment of Chemistry, Hunter College of the City University of New York, 695 Park Avenue, New York, New York 10065, USA. cdrain@hunter.cuny.edu.ORCID http://orcid.org/0000-0002-2568-4643
Julia RozenbergDepartment of Chemistry, Hunter College of the City University of New York, 695 Park Avenue, New York, New York 10065, USA. cdrain@hunter.cuny.edu.
Nancy L GreenbaumDepartment of Chemistry, Hunter College of the City University of New York, 695 Park Avenue, New York, New York 10065, USA. cdrain@hunter.cuny.edu and Chemistry Program, Graduate Center of the City University of New York, 365 5th Avenue, New York, New York 10016, USA.
Charles Michael DrainDepartment of Chemistry, Hunter College of the City University of New York, 695 Park Avenue, New York, New York 10065, USA. cdrain@hunter.cuny.edu and Chemistry Program, Graduate Center of the City University of New York, 365 5th Avenue, New York, New York 10016, USA and Rockefeller University, 1230 York Avenue, New York, New York 10065, USA.

Funding

RISE Program Hunter College Option IIIR25GM060665 · NIGMS · HUNTER COLLEGE · PI ORTIZ, BENJAMIN D.,, SERRANO, PETER A · 2000 to 2022
$22.8M
Basic and Translational Research Center for Reducing Health DisparitiesG12MD007599 · NIMHD · HUNTER COLLEGE · PI ANGULO, JESUS A · 2012 to 2017
$14.6M
BP-ENDURE at HunterR25GM097634 · NIGMS · HUNTER COLLEGE · PI MIRANDA, REGINA, QUINONES-JENAB, VANYA · 2010 to 2011
$1.1M
Clinical and Translational Science CenterTL1TR000459 · NCATS · WEILL MEDICAL COLL OF CORNELL UNIV · PI IMPERATO-MCGINLEY, JULIANNE L · 2012 to 2016
$451k
NCATS NIH HHS TL1 TR000459NIGMS NIH HHS R25 GM060665NIGMS NIH HHS R25 GM097634NIMHD NIH HHS G12 MD007599
6 · The paper itself

Abstract

A multifunctional chlorin platform appended with four short polyethylene glycols and a carboxylate-linker allows rapid conjugation to biotargeting motifs such as proteins and oligonucleotides. The stability and photophysical properties of the chlorin enable development of diagnostics, imaging, molecular tracking, and theranostics.

Indexed as

Click ChemistryMolecular StructureOligonucleotidesPorphyrinsProteinschlorinOligonucleotidesPorphyrinsProteins

Identifiers

PMID28304032
PMCPMC5463999

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.